eF-site/Summary 4r7t-C

eF-site ID	4r7t-C
PDB Code	4r7t
Chain	C

click to enlarge

Title	Crystal structure of glucosamine-6-phosphate deaminase from Vibrio cholerae
Classification	HYDROLASE
Compound	Glucosamine-6-phosphate deaminase
Source	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (NAGB_VIBCH)

Sequence	C:	MRLIPLKAAAQVGKWAAAHIVKRINEFQPTAERPFVLGLP TGGTPLATYKALIEMHKAGEVSFKHVVTFNMDEYVGLAAD HPESYRSFMYNNFFNHIDIQEENINLLNGNTDDHEAECKR YEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRIK TLTEDTRIANSRFFDINQVPKYALTIGVGTLLDAQEIMIL VTGHNKALALQAAVEGSVNHLWTVSALQLHPKAVIVCDEP STQELKVKTVKYFTELEAKNIVGF

Description

Functional site


1)	chain	C
	residue	141
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE GOL A 303
	source	: AC3

2)	chain	C
	residue	149
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE GOL A 303
	source	: AC3

3)	chain	C
	residue	112
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE MG B 300
	source	: AC4

4)	chain	C
	residue	97
	type
	sequence	I
	description	BINDING SITE FOR RESIDUE MG C 300
	source	: AC6

5)	chain	C
	residue	72
	type	ACT_SITE
	sequence	D
	description	Proton acceptor; for enolization step => ECO:0000255\|HAMAP-Rule:MF_01241
	source	Swiss-Prot : SWS_FT_FI1

6)	chain	C
	residue	141
	type	ACT_SITE
	sequence	D
	description	For ring-opening step => ECO:0000255\|HAMAP-Rule:MF_01241
	source	Swiss-Prot : SWS_FT_FI2

7)	chain	C
	residue	148
	type	ACT_SITE
	sequence	E
	description	For ring-opening step => ECO:0000255\|HAMAP-Rule:MF_01241
	source	Swiss-Prot : SWS_FT_FI2

8)	chain	C
	residue	143
	type	ACT_SITE
	sequence	H
	description	Proton acceptor; for ring-opening step => ECO:0000255\|HAMAP-Rule:MF_01241
	source	Swiss-Prot : SWS_FT_FI3

9)	chain	C
	residue	151
	type	SITE
	sequence	S
	description	Part of the allosteric site => ECO:0000255\|HAMAP-Rule:MF_01241
	source	Swiss-Prot : SWS_FT_FI4

10)	chain	C
	residue	158
	type	SITE
	sequence	R
	description	Part of the allosteric site => ECO:0000255\|HAMAP-Rule:MF_01241
	source	Swiss-Prot : SWS_FT_FI4

11)	chain	C
	residue	160
	type	SITE
	sequence	K
	description	Part of the allosteric site => ECO:0000255\|HAMAP-Rule:MF_01241
	source	Swiss-Prot : SWS_FT_FI4

12)	chain	C
	residue	161
	type	SITE
	sequence	T
	description	Part of the allosteric site => ECO:0000255\|HAMAP-Rule:MF_01241
	source	Swiss-Prot : SWS_FT_FI4

13)	chain	C
	residue	254
	type	SITE
	sequence	Y
	description	Part of the allosteric site => ECO:0000255\|HAMAP-Rule:MF_01241
	source	Swiss-Prot : SWS_FT_FI4