|
|
eF-site ID
|
4r18-N |
|
PDB Code
|
4r18 |
|
Chain
|
N |
|
click to enlarge
|
|
|
Title
|
Ligand-induced Lys33-Thr1 crosslinking at subunit beta5 of the yeast 20S proteasome |
|
Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
|
Compound
|
PROTEASOME SUBUNIT ALPHA TYPE-2 |
|
Source
|
ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae S288c; |
|
|
Sequence
|
N: |
TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDK
IWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAAS
VFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVH
KLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLS
QAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
N |
| residue |
51 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG H 301
|
| source |
: AC2
|
|
|
2)
|
chain |
N |
| residue |
19 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE MG N 201
|
| source |
: AC9
|
|
|
3)
|
chain |
N |
| residue |
163 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE MG N 201
|
| source |
: AC9
|
|
|
4)
|
chain |
N |
| residue |
166 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG N 201
|
| source |
: AC9
|
|
|
5)
|
chain |
N |
| residue |
169 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE MG N 201
|
| source |
: AC9
|
|
|
6)
|
chain |
N |
| residue |
1 |
| type |
ACT_SITE |
| sequence |
T
|
| description |
Nucleophile => ECO:0000269|PubMed:9087403
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|