|
|
eF-site ID
|
4r17-N |
|
PDB Code
|
4r17 |
|
Chain
|
N |
|
click to enlarge
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Title
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Ligand-induced aziridine-formation at subunit beta5 of the yeast 20S proteasome |
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Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
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Compound
|
Proteasome subunit alpha type-2 |
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Source
|
ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae S288c; |
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Sequence
|
N: |
TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDK
IWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAAS
VFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVH
KLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLS
QAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL
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Description
|
|
Functional site
|
|
|
1)
|
chain |
N |
| residue |
163 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE MG N 201
|
| source |
: AC9
|
|
|
2)
|
chain |
N |
| residue |
166 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG N 201
|
| source |
: AC9
|
|
|
3)
|
chain |
N |
| residue |
169 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE MG N 201
|
| source |
: AC9
|
|
|
4)
|
chain |
N |
| residue |
1 |
| type |
ACT_SITE |
| sequence |
T
|
| description |
Nucleophile => ECO:0000269|PubMed:9087403
|
| source |
Swiss-Prot : SWS_FT_FI1
|
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