eF-site ID 4r0s-A PDB Code 4r0s Chain A click to enlarge Title Crystal structure of P. aeruginosa TpbA Classification HYDROLASE Compound Protein tyrosine phosphatase TpbA Source Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (Q9HXC7_PSEAE) Sequence A:  TRSPAWAQAVDPSINLYRMSPTLYRSALPNAQSVALLQRL QVKTVVSFIKDDDRAWLGQAPVRVLSLPTHADRVDDAEVL SVLRQLQAAEREGPVLMHCKHGNNRTGLFAAMYRIVVQGW DKQAALEEMQHGGFGDEDDMRDASAYVRGADVDGLRLAMA NG Description Functional site 1) chain A residue 132 type sequence C description BINDING SITE FOR RESIDUE PO4 A 301 source : AC1 2) chain A residue 133 type sequence K description BINDING SITE FOR RESIDUE PO4 A 301 source : AC1 3) chain A residue 134 type sequence H description BINDING SITE FOR RESIDUE PO4 A 301 source : AC1 4) chain A residue 136 type sequence N description BINDING SITE FOR RESIDUE PO4 A 301 source : AC1 5) chain A residue 137 type sequence N description BINDING SITE FOR RESIDUE PO4 A 301 source : AC1 6) chain A residue 138 type sequence R description BINDING SITE FOR RESIDUE PO4 A 301 source : AC1 7) chain A residue 130-140 type prosite sequence MHCKHGNNRTG description TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. MHCkhGnnRTG source prosite : PS00383 8) chain A residue 105 type ACT_SITE sequence D description Proton donor/acceptor => ECO:0000305|PubMed:25909591 source Swiss-Prot : SWS_FT_FI1 9) chain A residue 132 type ACT_SITE sequence C description Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160, ECO:0000305|PubMed:25909591 source Swiss-Prot : SWS_FT_FI2

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