|
|
eF-site ID
|
4qz0-J |
|
PDB Code
|
4qz0 |
|
Chain
|
J |
|
click to enlarge
|
|
|
Title
|
yCP beta5-M45V mutant in complex with the epoxyketone inhibitor ONX 0914 |
|
Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
|
Compound
|
Proteasome subunit alpha type-2 |
|
Source
|
ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
|
|
Sequence
|
J: |
MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSP
HTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAV
SSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID
YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL
LKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDF
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
J |
| residue |
23 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE MES K 303
|
| source |
: AC7
|
|
|
2)
|
chain |
J |
| residue |
5-52 |
| type |
prosite |
| sequence |
LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLM
SFAGEAGD
|
| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGVkFnnGVVIAADtrstqgpivadknca.KlhrispkiwcagaGtaAD
|
| source |
prosite : PS00854
|
|
|
|