eF-site ID 4qxg-HL PDB Code 4qxg Chain H, L click to enlarge Title Antigen binding fragment of an anti IFNAR1 antibody Classification IMMUNE SYSTEM Compound Fab, heavy chain, IgG1 Source (4QXG) Sequence H:  EVQLVQSGAEVKKPGESLKISCKGSGYIFTNYWIAWVRQM PGKGLESMGIIYPGDSDIRYSPSFQGQVTISADKSITTAY LQWSSLKASDTAMYYCARHDIEGFDYWGRGTLVTVSSAST KGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC NVNHKPSNTKVDKRVEPK L:  EIVLTQSPGTLSLSPGERATLSCRASQSVSSSFFAWYQQK PGQAPRLLIYGASSRATGIPDRLSGSGSGTDFTLTITRLE PEDFAVYYCQQYDSSAITFGQGTRLEIKRTVAAPSVFIFP PSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQ GLSSPVTKSFNRGE Description (1)  Fab, heavy chain, IgG1, Fab, light chain, IgG1 Functional site 1) chain H residue 15 type sequence G description BINDING SITE FOR RESIDUE K H 301 source : AC1 2) chain H residue 84 type sequence S description BINDING SITE FOR RESIDUE K H 301 source : AC1 3) chain H residue 85 type sequence S description BINDING SITE FOR RESIDUE K H 301 source : AC1 4) chain H residue 170 type sequence F description BINDING SITE FOR RESIDUE GOL L 301 source : AC2 5) chain H residue 171 type sequence P description BINDING SITE FOR RESIDUE GOL L 301 source : AC2 6) chain H residue 181 type sequence S description BINDING SITE FOR RESIDUE GOL L 301 source : AC2 7) chain H residue 182 type sequence L description BINDING SITE FOR RESIDUE GOL L 301 source : AC2 8) chain H residue 183 type sequence S description BINDING SITE FOR RESIDUE GOL L 301 source : AC2 9) chain L residue 161 type sequence Q description BINDING SITE FOR RESIDUE GOL L 301 source : AC2 10) chain L residue 163 type sequence S description BINDING SITE FOR RESIDUE GOL L 301 source : AC2 11) chain L residue 177 type sequence S description BINDING SITE FOR RESIDUE GOL L 301 source : AC2 12) chain L residue 178 type sequence S description BINDING SITE FOR RESIDUE GOL L 301 source : AC2 13) chain L residue 179 type sequence T description BINDING SITE FOR RESIDUE GOL L 301 source : AC2 14) chain L residue 94 type sequence S description BINDING SITE FOR RESIDUE PO4 L 302 source : AC3 15) chain L residue 95 type sequence S description BINDING SITE FOR RESIDUE PO4 L 302 source : AC3 16) chain H residue 198-204 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290 17) chain L residue 193-199 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290

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