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eF-site ID
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4qwx-a |
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PDB Code
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4qwx |
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Chain
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a |
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click to enlarge
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Title
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yCP in complex with the epoxyketone inhibitor ONX 0914 |
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Classification
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HYDROLASE/HYDROLASE INHIBITOR |
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Compound
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PROTEASOME SUBUNIT ALPHA TYPE-2 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
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a: |
TQQPIVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVE
RLIPVGDNTVVGISGDISDMQHIERLLKDLVTENAYDNPL
ADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGVQ
SNGDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVD
RESDIPKTTVQVAEEAIVNAMRVLYYRDARSSRNFSLAII
DKNTGLTFKKNLQVENMKWDFAKDIKGYGTQKI
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Description
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Functional site
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1)
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chain |
a |
| residue |
34 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE MG N 202
|
| source |
: BC2
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2)
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chain |
a |
| residue |
12-59 |
| type |
prosite |
| sequence |
ISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVV
GISGDISD
|
| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGVkFnnGVVIAADtrstqgpivadknca.KlhrispkiwcagaGtaAD
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| source |
prosite : PS00854
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