eF-site ID 4qwx-Y PDB Code 4qwx Chain Y click to enlarge Title yCP in complex with the epoxyketone inhibitor ONX 0914 Classification HYDROLASE/HYDROLASE INHIBITOR Compound PROTEASOME SUBUNIT ALPHA TYPE-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence Y:  TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPF LLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAAS KILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRS ILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKV KEEEGSFNNVIG Description Functional site 1) chain Y residue 1 type sequence T description BINDING SITE FOR RESIDUE 04C Y 301 source : BC8 2) chain Y residue 19 type sequence R description BINDING SITE FOR RESIDUE 04C Y 301 source : BC8 3) chain Y residue 20 type sequence A description BINDING SITE FOR RESIDUE 04C Y 301 source : BC8 4) chain Y residue 21 type sequence T description BINDING SITE FOR RESIDUE 04C Y 301 source : BC8 5) chain Y residue 31 type sequence V description BINDING SITE FOR RESIDUE 04C Y 301 source : BC8 6) chain Y residue 33 type sequence K description BINDING SITE FOR RESIDUE 04C Y 301 source : BC8 7) chain Y residue 47 type sequence G description BINDING SITE FOR RESIDUE 04C Y 301 source : BC8 8) chain Y residue 48 type sequence G description BINDING SITE FOR RESIDUE 04C Y 301 source : BC8 9) chain Y residue 49 type sequence A description BINDING SITE FOR RESIDUE 04C Y 301 source : BC8 10) chain Y residue 170 type sequence Y description BINDING SITE FOR RESIDUE 04C Y 301 source : BC8 11) chain Y residue 165 type sequence A description BINDING SITE FOR RESIDUE MG Y 302 source : BC9 12) chain Y residue 166 type sequence H description BINDING SITE FOR RESIDUE MG Y 302 source : BC9 13) chain Y residue 168 type sequence D description BINDING SITE FOR RESIDUE MG Y 302 source : BC9 14) chain Y residue 169 type sequence A description BINDING SITE FOR RESIDUE MG Y 302 source : BC9 15) chain Y residue 171 type sequence S description BINDING SITE FOR RESIDUE MG Y 302 source : BC9 16) chain Y residue 21 type sequence T description BINDING SITE FOR RESIDUE NA Y 303 source : CC1 17) chain Y residue 1 type sequence T description BINDING SITE FOR RESIDUE MES Y 304 source : CC2 18) chain Y residue 47 type sequence G description BINDING SITE FOR RESIDUE MES Y 304 source : CC2 19) chain Y residue 96 type sequence S description BINDING SITE FOR RESIDUE MES Y 304 source : CC2 20) chain Y residue 97 type sequence M description BINDING SITE FOR RESIDUE MES Y 304 source : CC2 21) chain Y residue 98 type sequence G description BINDING SITE FOR RESIDUE MES Y 304 source : CC2 22) chain Y residue 130 type sequence G description BINDING SITE FOR RESIDUE MES Y 304 source : CC2 23) chain Y residue 131 type sequence S description BINDING SITE FOR RESIDUE MES Y 304 source : CC2 24) chain Y residue 49 type BINDING sequence A description source Swiss-Prot : SWS_FT_FI2

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