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eF-site ID
|
4qwx-X |
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PDB Code
|
4qwx |
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Chain
|
X |
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click to enlarge
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Title
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yCP in complex with the epoxyketone inhibitor ONX 0914 |
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Classification
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HYDROLASE/HYDROLASE INHIBITOR |
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Compound
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PROTEASOME SUBUNIT ALPHA TYPE-2 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
|
X: |
MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSP
HTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAV
SSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID
YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL
LKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDF
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Description
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Functional site
|
|
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1)
|
chain |
X |
| residue |
118 |
| type |
|
| sequence |
Q
|
| description |
BINDING SITE FOR RESIDUE MG X 201
|
| source |
: BC7
|
|
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2)
|
chain |
X |
| residue |
124 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE MG X 201
|
| source |
: BC7
|
|
|
3)
|
chain |
X |
| residue |
23 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE MES Y 304
|
| source |
: CC2
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