eF-site ID 4qwx-N PDB Code 4qwx Chain N click to enlarge Title yCP in complex with the epoxyketone inhibitor ONX 0914 Classification HYDROLASE/HYDROLASE INHIBITOR Compound PROTEASOME SUBUNIT ALPHA TYPE-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence N:  TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDK IWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAAS VFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVH KLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLS QAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL Description Functional site 1) chain N residue 1 type sequence T description BINDING SITE FOR RESIDUE 04C N 201 source : BC1 2) chain N residue 19 type sequence R description BINDING SITE FOR RESIDUE 04C N 201 source : BC1 3) chain N residue 20 type sequence T description BINDING SITE FOR RESIDUE 04C N 201 source : BC1 4) chain N residue 21 type sequence T description BINDING SITE FOR RESIDUE 04C N 201 source : BC1 5) chain N residue 31 type sequence T description BINDING SITE FOR RESIDUE 04C N 201 source : BC1 6) chain N residue 45 type sequence R description BINDING SITE FOR RESIDUE 04C N 201 source : BC1 7) chain N residue 46 type sequence S description BINDING SITE FOR RESIDUE 04C N 201 source : BC1 8) chain N residue 47 type sequence G description BINDING SITE FOR RESIDUE 04C N 201 source : BC1 9) chain N residue 49 type sequence A description BINDING SITE FOR RESIDUE 04C N 201 source : BC1 10) chain N residue 168 type sequence S description BINDING SITE FOR RESIDUE 04C N 201 source : BC1 11) chain N residue 19 type sequence R description BINDING SITE FOR RESIDUE MG N 202 source : BC2 12) chain N residue 163 type sequence I description BINDING SITE FOR RESIDUE MG N 202 source : BC2 13) chain N residue 166 type sequence D description BINDING SITE FOR RESIDUE MG N 202 source : BC2 14) chain N residue 169 type sequence S description BINDING SITE FOR RESIDUE MG N 202 source : BC2 15) chain N residue 1 type ACT_SITE sequence T description Nucleophile => ECO:0000269|PubMed:9087403 source Swiss-Prot : SWS_FT_FI1

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