eF-site ID 4qwu-Y PDB Code 4qwu Chain Y click to enlarge Title yCP beta5-C52F mutant in complex with bortezomib Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome subunit alpha type-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence Y:  TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPF LLGTMAGGAADFQFWETWLGSQCRLHELREKERISVAAAS KILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRS ILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKV KEEEGSFNNVIG Description Functional site 1) chain Y residue 1 type sequence T description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC4 2) chain Y residue 20 type sequence A description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC4 3) chain Y residue 21 type sequence T description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC4 4) chain Y residue 45 type sequence M description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC4 5) chain Y residue 47 type sequence G description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC4 6) chain Y residue 48 type sequence G description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC4 7) chain Y residue 49 type sequence A description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC4 8) chain Y residue 170 type sequence Y description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC4 9) chain Y residue 165 type sequence A description BINDING SITE FOR RESIDUE MG Y 302 source : BC5 10) chain Y residue 168 type sequence D description BINDING SITE FOR RESIDUE MG Y 302 source : BC5 11) chain Y residue 169 type sequence A description BINDING SITE FOR RESIDUE MG Y 302 source : BC5 12) chain Y residue 171 type sequence S description BINDING SITE FOR RESIDUE MG Y 302 source : BC5 13) chain Y residue 49 type BINDING sequence A description source Swiss-Prot : SWS_FT_FI2

Display surface Download Links