|
|
eF-site ID
|
4qwu-A |
|
PDB Code
|
4qwu |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
yCP beta5-C52F mutant in complex with bortezomib |
|
Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
|
Compound
|
Proteasome subunit alpha type-2 |
|
Source
|
ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
|
|
Sequence
|
A: |
MTDRYSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKAT
NGVVIATEKKSSSPLAMSETLSKVSLLTPDIGAVYSGMGP
DYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQE
ATQSGGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWK
ATAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKESV
EGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTS
QEINDRLEAL
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
5-27 |
| type |
prosite |
| sequence |
YSFSLTTFSPSGKLGQIDYALTA
|
| description |
PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdralSiFSPdGHifQVEYAleA
|
| source |
prosite : PS00388
|
|
|
|