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eF-site ID
|
4qvy-W |
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PDB Code
|
4qvy |
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Chain
|
W |
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click to enlarge
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Title
|
yCP beta5-A49T-mutant in complex with bortezomib |
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Classification
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HYDROLASE/HYDROLASE INHIBITOR |
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Compound
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PROTEASOME SUBUNIT ALPHA TYPE-2 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
|
W: |
SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFE
KIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERA
IEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFI
AGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPE
DLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLK
MRQD
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Description
|
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Functional site
|
|
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1)
|
chain |
W |
| residue |
204 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG K 302
|
| source |
: AC7
|
|
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2)
|
chain |
W |
| residue |
124 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE BO2 V 301
|
| source |
: BC4
|
|
|
3)
|
chain |
W |
| residue |
128 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE BO2 V 301
|
| source |
: BC4
|
|
|
4)
|
chain |
W |
| residue |
69 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
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