|
|
eF-site ID
|
4qvq-a |
|
PDB Code
|
4qvq |
|
Chain
|
a |
|
click to enlarge
|
|
|
Title
|
yCP beta5-M45I mutant in complex with bortezomib |
|
Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
|
Compound
|
Proteasome subunit alpha type-2 |
|
Source
|
ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
|
|
Sequence
|
a: |
TQQPIVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVE
RLIPVGDNTVVGISGDISDMQHIERLLKDLVTENAYDNPL
ADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGVQ
SNGDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVD
RESDIPKTTVQVAEEAIVNAMRVLYYRDARSSRNFSLAII
DKNTGLTFKKNLQVENMKWDFAKDIKGYGTQKI
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
a |
| residue |
12-59 |
| type |
prosite |
| sequence |
ISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVV
GISGDISD
|
| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. ISMkYdnGVIIAADnlgsygsllrfngve.RlipvgdntvvgisGdiSD
|
| source |
prosite : PS00854
|
|
|
|