eF-site ID 4qvp-Y PDB Code 4qvp Chain Y click to enlarge Title yCP beta5-M45T mutant in complex with bortezomib Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome subunit alpha type-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence Y:  TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPF LLGTTAGGAADCQFWETWLGSQCRLHELREKERISVAAAS KILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRS ILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKV KEEEGSFNNVIG Description Functional site 1) chain Y residue 1 type sequence T description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC6 2) chain Y residue 20 type sequence A description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC6 3) chain Y residue 21 type sequence T description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC6 4) chain Y residue 45 type sequence T description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC6 5) chain Y residue 47 type sequence G description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC6 6) chain Y residue 49 type sequence A description BINDING SITE FOR RESIDUE BO2 Y 301 source : BC6 7) chain Y residue 19 type sequence R description BINDING SITE FOR RESIDUE MG Y 302 source : BC7 8) chain Y residue 165 type sequence A description BINDING SITE FOR RESIDUE MG Y 302 source : BC7 9) chain Y residue 168 type sequence D description BINDING SITE FOR RESIDUE MG Y 302 source : BC7 10) chain Y residue 171 type sequence S description BINDING SITE FOR RESIDUE MG Y 302 source : BC7 11) chain Y residue 49 type BINDING sequence A description source Swiss-Prot : SWS_FT_FI2

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