|
|
eF-site ID
|
4qvp-W |
|
PDB Code
|
4qvp |
|
Chain
|
W |
|
click to enlarge
|
|
|
Title
|
yCP beta5-M45T mutant in complex with bortezomib |
|
Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
|
Compound
|
Proteasome subunit alpha type-2 |
|
Source
|
ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
|
|
Sequence
|
W: |
SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFE
KIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERA
IEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFI
AGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPE
DLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLK
MRQD
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
W |
| residue |
204 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG K 302
|
| source |
: AC7
|
|
|
2)
|
chain |
W |
| residue |
69 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|