eF-site ID 4qtu-ABCD PDB Code 4qtu Chain A, B, C, D click to enlarge Title Structure of S. cerevisiae Bud23-Trm112 complex involved in formation of m7G1575 on 18S rRNA (SAM bound form) Classification TRANSFERASE Compound Multifunctional methyltransferase subunit TRM112 Source Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (BUD23_YEAST) Sequence A:  MKFLTTNFLKCSVKACDTSNDNFPLQYDGSKCQLVQDESI EFNPEFLLNIVDRVDWPAVLTVAAELGNNALPPTKPSFPS SIQELTDDDMAILNDLHTLLLQTSIAEGEMKCRNCGHIYY IKNGIPNLLLPPHL B:  IFYNDSEAHKYTGSTRVQHIQAKMTLRALELLNLQPCSFI LDIGCGSGLSGEILTQEGDHVWCGLDISPSMLATGLSREL EGDLMLQDMGTGIPFRAGSFDAAISISAIQWLXNADTSYN DPKQRLMRFFNTLYAALKKGGKFVAQFYPKNDDQVDDILQ SAKVAGFSGGLVVDDPESKKNKKYYLVLSSG C:  MKFLTTNFLKCSVKACDTSNDNFPLQYDGSKCQLVQDESI EFNPEFLLNIVDRVDWPAVLTVAAELGNNALPPTKPSFPS SIQELTDDDMAILNDLHTLLLQTSIAEGEMKCRNCGHIYY IKNGIPNLLLPPHLV D:  EAHKYTGSTRVQHIQAKMTLRALELLNLQPCSFILDIGCG SGLSGEILTQEGDHVWCGLDISPSMLATGLSRELEGDLML QDMGTGIPFRAGSFDAAISISAIQWLXNDPKQRLMRFFNT LYAALKKGGKFVAQFYPKNDDQVDDILQSAKVAGFSGGLV VDDPESKKNKKYYLVLSSG Description Functional site 1) chain A residue 11 type sequence C description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 2) chain A residue 16 type sequence C description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 3) chain A residue 112 type sequence C description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 4) chain A residue 115 type sequence C description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 5) chain A residue 14 type sequence K description BINDING SITE FOR RESIDUE EDO A 202 source : AC2 6) chain A residue 134 type sequence L description BINDING SITE FOR RESIDUE EDO A 202 source : AC2 7) chain B residue 139 type sequence R description BINDING SITE FOR RESIDUE EDO A 202 source : AC2 8) chain A residue 36 type sequence Q description BINDING SITE FOR RESIDUE EDO A 203 source : AC3 9) chain A residue 117 type sequence H description BINDING SITE FOR RESIDUE EDO A 204 source : AC4 10) chain A residue 118 type sequence I description BINDING SITE FOR RESIDUE EDO A 204 source : AC4 11) chain A residue 119 type sequence Y description BINDING SITE FOR RESIDUE EDO A 204 source : AC4 12) chain A residue 120 type sequence Y description BINDING SITE FOR RESIDUE EDO A 204 source : AC4 13) chain A residue 127 type sequence N description BINDING SITE FOR RESIDUE EDO A 204 source : AC4 14) chain A residue 129 type sequence L description BINDING SITE FOR RESIDUE EDO A 204 source : AC4 15) chain A residue 48 type sequence L description BINDING SITE FOR RESIDUE EDO A 205 source : AC5 16) chain A residue 52 type sequence D description BINDING SITE FOR RESIDUE EDO A 205 source : AC5 17) chain A residue 78 type sequence F description BINDING SITE FOR RESIDUE EDO A 205 source : AC5 18) chain A residue 79 type sequence P description BINDING SITE FOR RESIDUE EDO A 205 source : AC5 19) chain A residue 87 type sequence D description BINDING SITE FOR RESIDUE EDO A 206 source : AC6 20) chain B residue 159 type sequence Y description BINDING SITE FOR RESIDUE EDO A 206 source : AC6 21) chain B residue 121 type sequence Q description BINDING SITE FOR RESIDUE EDO A 207 source : AC7 22) chain B residue 122 type sequence W description BINDING SITE FOR RESIDUE EDO A 207 source : AC7 23) chain B residue 161 type sequence K description BINDING SITE FOR RESIDUE EDO A 207 source : AC7 24) chain B residue 22 type sequence Y description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 25) chain B residue 32 type sequence Q description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 26) chain B residue 55 type sequence G description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 27) chain B residue 56 type sequence C description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 28) chain B residue 57 type sequence G description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 29) chain B residue 60 type sequence L description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 30) chain B residue 61 type sequence S description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 31) chain B residue 77 type sequence D description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 32) chain B residue 78 type sequence I description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 33) chain B residue 79 type sequence S description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 34) chain B residue 82 type sequence M description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 35) chain B residue 98 type sequence Q description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 36) chain B residue 99 type sequence D description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 37) chain B residue 100 type sequence M description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 38) chain B residue 117 type sequence I description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 39) chain B residue 118 type sequence S description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 40) chain B residue 119 type sequence A description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 41) chain B residue 122 type sequence W description BINDING SITE FOR RESIDUE SAM B 301 source : AC8 42) chain A residue 86 type sequence T description BINDING SITE FOR RESIDUE EDO B 302 source : AC9 43) chain A residue 87 type sequence D description BINDING SITE FOR RESIDUE EDO B 302 source : AC9 44) chain A residue 88 type sequence D description BINDING SITE FOR RESIDUE EDO B 302 source : AC9 45) chain B residue 139 type sequence R description BINDING SITE FOR RESIDUE EDO B 303 source : BC1 46) chain B residue 142 type sequence N description BINDING SITE FOR RESIDUE EDO B 303 source : BC1 47) chain B residue 170 type sequence L description BINDING SITE FOR RESIDUE EDO B 304 source : BC2 48) chain B residue 174 type sequence K description BINDING SITE FOR RESIDUE EDO B 304 source : BC2 49) chain B residue 178 type sequence F description BINDING SITE FOR RESIDUE EDO B 304 source : BC2 50) chain B residue 179 type sequence S description BINDING SITE FOR RESIDUE EDO B 304 source : BC2 51) chain B residue 180 type sequence G description BINDING SITE FOR RESIDUE EDO B 304 source : BC2 52) chain D residue 186 type sequence D description BINDING SITE FOR RESIDUE EDO B 304 source : BC2 53) chain D residue 188 type sequence E description BINDING SITE FOR RESIDUE EDO B 304 source : BC2 54) chain B residue 188 type sequence E description BINDING SITE FOR RESIDUE EDO B 305 source : BC3 55) chain D residue 170 type sequence L description BINDING SITE FOR RESIDUE EDO B 305 source : BC3 56) chain D residue 180 type sequence G description BINDING SITE FOR RESIDUE EDO B 305 source : BC3 57) chain B residue 25 type sequence S description BINDING SITE FOR RESIDUE EDO B 306 source : BC4 58) chain B residue 26 type sequence T description BINDING SITE FOR RESIDUE EDO B 306 source : BC4 59) chain B residue 27 type sequence R description BINDING SITE FOR RESIDUE EDO B 306 source : BC4 60) chain B residue 67 type sequence Q description BINDING SITE FOR RESIDUE EDO B 307 source : BC5 61) chain B residue 68 type sequence E description BINDING SITE FOR RESIDUE EDO B 307 source : BC5 62) chain A residue 43 type sequence N description BINDING SITE FOR RESIDUE EDO B 308 source : BC6 63) chain B residue 70 type sequence D description BINDING SITE FOR RESIDUE EDO B 308 source : BC6 64) chain B residue 71 type sequence H description BINDING SITE FOR RESIDUE EDO B 308 source : BC6 65) chain B residue 72 type sequence V description BINDING SITE FOR RESIDUE EDO B 308 source : BC6 66) chain B residue 92 type sequence E description BINDING SITE FOR RESIDUE EDO B 308 source : BC6 67) chain B residue 45 type sequence L description BINDING SITE FOR RESIDUE EDO B 309 source : BC7 68) chain B residue 68 type sequence E description BINDING SITE FOR RESIDUE EDO B 309 source : BC7 69) chain B residue 71 type sequence H description BINDING SITE FOR RESIDUE EDO B 309 source : BC7 70) chain B residue 12 type sequence I description BINDING SITE FOR RESIDUE EDO B 310 source : BC8 71) chain B residue 14 type sequence Y description BINDING SITE FOR RESIDUE EDO B 310 source : BC8 72) chain B residue 79 type sequence S description BINDING SITE FOR RESIDUE EDO B 310 source : BC8 73) chain B residue 80 type sequence P description BINDING SITE FOR RESIDUE EDO B 310 source : BC8 74) chain B residue 81 type sequence S description BINDING SITE FOR RESIDUE EDO B 310 source : BC8 75) chain B residue 38 type sequence R description BINDING SITE FOR RESIDUE EDO B 311 source : BC9 76) chain D residue 198 type sequence V description BINDING SITE FOR RESIDUE EDO B 311 source : BC9 77) chain C residue 11 type sequence C description BINDING SITE FOR RESIDUE ZN C 201 source : CC1 78) chain C residue 16 type sequence C description BINDING SITE FOR RESIDUE ZN C 201 source : CC1 79) chain C residue 112 type sequence C description BINDING SITE FOR RESIDUE ZN C 201 source : CC1 80) chain C residue 115 type sequence C description BINDING SITE FOR RESIDUE ZN C 201 source : CC1 81) chain A residue 18 type sequence T description BINDING SITE FOR RESIDUE EDO C 202 source : CC2 82) chain A residue 19 type sequence S description BINDING SITE FOR RESIDUE EDO C 202 source : CC2 83) chain A residue 20 type sequence N description BINDING SITE FOR RESIDUE EDO C 202 source : CC2 84) chain A residue 21 type sequence D description BINDING SITE FOR RESIDUE EDO C 202 source : CC2 85) chain C residue 75 type sequence K description BINDING SITE FOR RESIDUE EDO C 202 source : CC2 86) chain C residue 77 type sequence S description BINDING SITE FOR RESIDUE EDO C 202 source : CC2 87) chain C residue 118 type sequence I description BINDING SITE FOR RESIDUE EDO C 203 source : CC3 88) chain C residue 119 type sequence Y description BINDING SITE FOR RESIDUE EDO C 203 source : CC3 89) chain C residue 120 type sequence Y description BINDING SITE FOR RESIDUE EDO C 203 source : CC3 90) chain C residue 127 type sequence N description BINDING SITE FOR RESIDUE EDO C 203 source : CC3 91) chain D residue 22 type sequence Y description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 92) chain D residue 32 type sequence Q description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 93) chain D residue 55 type sequence G description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 94) chain D residue 56 type sequence C description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 95) chain D residue 57 type sequence G description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 96) chain D residue 60 type sequence L description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 97) chain D residue 61 type sequence S description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 98) chain D residue 77 type sequence D description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 99) chain D residue 78 type sequence I description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 100) chain D residue 79 type sequence S description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 101) chain D residue 82 type sequence M description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 102) chain D residue 98 type sequence Q description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 103) chain D residue 99 type sequence D description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 104) chain D residue 100 type sequence M description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 105) chain D residue 117 type sequence I description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 106) chain D residue 118 type sequence S description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 107) chain D residue 122 type sequence W description BINDING SITE FOR RESIDUE SAM D 301 source : CC4 108) chain B residue 183 type sequence V description BINDING SITE FOR RESIDUE EDO D 302 source : CC5 109) chain B residue 198 type sequence V description BINDING SITE FOR RESIDUE EDO D 302 source : CC5 110) chain D residue 38 type sequence R description BINDING SITE FOR RESIDUE EDO D 302 source : CC5

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