eF-site ID 4qto-A PDB Code 4qto Chain A click to enlarge Title 1.65 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) from Staphylococcus aureus with BME-modified Cys289 and PEG molecule in active site Classification OXIDOREDUCTASE Compound Betaine aldehyde dehydrogenase Source (Q5HCU0_STAAC) Sequence A:  AMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFT VSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAI ADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYF AGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYP LLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEV GFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGK HIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALN GGYFHAGQVXSAGSRILVQNSIKDKFEQALIDRVKKIKLG NGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGK RPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVE GFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKL GTVWINDFHPYFAQAPWGGYKQSGIGRELGKEGLEEYLVS KHILTNTNPQLVNWFSK Description Functional site 1) chain A residue 460 type sequence K description BINDING SITE FOR RESIDUE NA A 501 source : AC1 2) chain A residue 463 type sequence G description BINDING SITE FOR RESIDUE NA A 501 source : AC1 3) chain A residue 283 type sequence F description BINDING SITE FOR RESIDUE PGE A 502 source : AC2 4) chain A residue 448 type sequence H description BINDING SITE FOR RESIDUE PGE A 502 source : AC2 5) chain A residue 450 type sequence Y description BINDING SITE FOR RESIDUE PGE A 502 source : AC2 6) chain A residue 342 type sequence S description BINDING SITE FOR RESIDUE PGE A 503 source : AC3 7) chain A residue 343 type sequence Y description BINDING SITE FOR RESIDUE PGE A 503 source : AC3 8) chain A residue 346 type sequence V description BINDING SITE FOR RESIDUE PGE A 503 source : AC3 9) chain A residue 385 type sequence R description BINDING SITE FOR RESIDUE PGE A 503 source : AC3 10) chain A residue 8 type sequence S description BINDING SITE FOR RESIDUE PEG A 504 source : AC4 11) chain A residue 17 type sequence W description BINDING SITE FOR RESIDUE PEG A 504 source : AC4 12) chain A residue 197 type sequence E description BINDING SITE FOR RESIDUE PEG A 504 source : AC4 13) chain A residue 155 type sequence P description BINDING SITE FOR RESIDUE PEG A 505 source : AC5 14) chain A residue 234 type sequence G description BINDING SITE FOR RESIDUE PEG A 505 source : AC5 15) chain A residue 289 type sequence X description BINDING SITE FOR RESIDUE PEG A 505 source : AC5 16) chain A residue 336 type sequence H description BINDING SITE FOR RESIDUE PEG A 505 source : AC5 17) chain A residue 392 type sequence F description BINDING SITE FOR RESIDUE PEG A 505 source : AC5 18) chain A residue 61 type sequence S description BINDING SITE FOR RESIDUE PEG A 506 source : AC6 19) chain A residue 62 type sequence G description BINDING SITE FOR RESIDUE PEG A 506 source : AC6 20) chain A residue 63 type sequence E description BINDING SITE FOR RESIDUE PEG A 506 source : AC6 21) chain A residue 103 type sequence E description BINDING SITE FOR RESIDUE TRS A 507 source : AC7 22) chain A residue 324 type sequence A description BINDING SITE FOR RESIDUE TRS A 507 source : AC7 23) chain A residue 326 type sequence T description BINDING SITE FOR RESIDUE TRS A 507 source : AC7 24) chain A residue 327 type sequence E description BINDING SITE FOR RESIDUE TRS A 507 source : AC7 25) chain A residue 249 type sequence V description BINDING SITE FOR RESIDUE NA B 501 source : AC8 26) chain A residue 493 type sequence W description BINDING SITE FOR RESIDUE TRS B 505 source : BC3 27) chain A residue 282-293 type prosite sequence YFHAGQVXSAGS description ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. YfHAGQVCSAGS source prosite : PS00070 28) chain A residue 254-261 type prosite sequence LELGGKNP description ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. LELGGKNP source prosite : PS00687

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