eF-site ID 4qqz-G PDB Code 4qqz Chain G click to enlarge Title Crystal structure of T. fusca Cas3-AMPPNP Classification Hydrolase/DNA Compound CRISPR-associated helicase, Cas3 family Source Thermobifida fusca (strain YX) (4QQZ) Sequence G:  PPLDLRFWAKERGLRGKTYPLVCHSLDAAAAALVLWNEYL SPGLRDTIASSMETDEEHAGHCIAFWAGLHDIGKLTREFQ QQIAIDLSAYPGEELSGEQRSHAAATGKWLPFALPSLGYP NGGLVTGLVAQMLGGHHGTFHPHPSFQSRNPLAEFGFSSP HWEKQRHALLHAVFDATGRPTPPDMLDGPTASVVCGLVIL ADWLVSQEDFLLERLTSLPADGSASALRAHFETSLRRIPS LLDAAGLRPITVPPATFTESFPHLSKPNGLQASLAKHLPC LCTGPGLVLITAPMGEGKTEAAYHVADLLGKATGRPGRFL ALPTMATADQMHTRLKEYARYRVENSSTLALLHSMAWLNP DYAPADPFAATDWLMGRKRGLLAPWAVGTIDQALMAVLRA KHNALRLFGLAGKVVVVDEAHAVDPYMQVLLEQLLRWLGT LDVPVVLLSATLHHSIANSLVKAYLEGARGRRWNRSEPQP VSEVSYPGWLHVDARIGKVTRSSDVDPLPIATTPRKPLEV RLVDVPVKEGALNRSTVLAKELTPLVKQGGCAAIICTTVA EAQGVYDLLSQWFATLGAPDLYLLHSRFPNRQRTEITATI VDLFGKEGAQSGRRPTRGAVLVATQVVEQSLDLDVDLMIS DLAPVSLLLQRAGRCWRHEHLGIINRPQWAKQPELVVLTP EQNRAPWFPRSWTSVYPLALLQRTYTLLRRRNGAPVQIPE DVQQLVDDVYDDDSLAEDLEADMERMGEELAQRGLARNAV IPDPDDAEDNLNGLTEFSVLATRFGAGSVRVLCYYVTAGN RWLDPECTVEFPEQGTGREGRFTMADCRDLVARTIPVRMG PWASQLTEDNHPPEAWRESFYLRDLVLIPQAVLPTETGGR EWLLDPCKGLIF Description Functional site 1) chain G residue 84 type sequence D description BINDING SITE FOR RESIDUE FE G 1001 source : BC1 2) chain G residue 115 type sequence H description BINDING SITE FOR RESIDUE FE G 1001 source : BC1 3) chain G residue 149 type sequence H description BINDING SITE FOR RESIDUE FE G 1001 source : BC1 4) chain G residue 150 type sequence H description BINDING SITE FOR RESIDUE FE G 1001 source : BC1 5) chain G residue 37 type sequence H description BINDING SITE FOR RESIDUE FE G 1002 source : BC2 6) chain G residue 83 type sequence H description BINDING SITE FOR RESIDUE FE G 1002 source : BC2 7) chain G residue 84 type sequence D description BINDING SITE FOR RESIDUE FE G 1002 source : BC2 8) chain G residue 215 type sequence D description BINDING SITE FOR RESIDUE FE G 1002 source : BC2 9) chain G residue 277 type sequence L description BINDING SITE FOR RESIDUE ANP G 1003 source : BC3 10) chain G residue 279 type sequence K description BINDING SITE FOR RESIDUE ANP G 1003 source : BC3 11) chain G residue 281 type sequence N description BINDING SITE FOR RESIDUE ANP G 1003 source : BC3 12) chain G residue 307 type sequence M description BINDING SITE FOR RESIDUE ANP G 1003 source : BC3 13) chain G residue 308 type sequence G description BINDING SITE FOR RESIDUE ANP G 1003 source : BC3 14) chain G residue 309 type sequence E description BINDING SITE FOR RESIDUE ANP G 1003 source : BC3 15) chain G residue 310 type sequence G description BINDING SITE FOR RESIDUE ANP G 1003 source : BC3 16) chain G residue 311 type sequence K description BINDING SITE FOR RESIDUE ANP G 1003 source : BC3 17) chain G residue 313 type sequence E description BINDING SITE FOR RESIDUE ANP G 1003 source : BC3 18) chain G residue 692 type sequence R description BINDING SITE FOR RESIDUE ANP G 1003 source : BC3

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