eF-site ID 4qqy-C PDB Code 4qqy Chain C click to enlarge Title Crystal structure of T. fusca Cas3-ADP Classification Hydrolase/DNA Compound CRISPR-associated helicase, Cas3 family Source Thermobifida fusca (strain YX) (4QQY) Sequence C:  PPLDLRFWAKERGLRGKTYPLVCHSLDAAAAALVLWNEYL SPGLRDTIASSMETDEEHAGHCIAFWAGLHDIGKLTREFQ QQIAIDLSAYPGEELSGEQRSHAAATGKWLPFALPSLGYP NGGLVTGLVAQMLGGHHGTFHPHPSFQSRNPLAEFGFSSP HWEKQRHALLHAVFDATGRPTPPDMLDGPTASVVCGLVIL ADWLVSQEDFLLERLTSLPADGSASALRAHFETSLRRIPS LLDAAGLRPITVPPATFTESFPHLSKPNGLQASLAKHLPC LCTGPGLVLITAPMGEGKTEAAYHVADLLGKATGRPGRFL ALPTMATADQMHTRLKEYARYRVENTRSSTLALLHSMAWL NPDYAPADPFAATDWLMGRKRGLLAPWAVGTIDQALMAVL RAKHNALRLFGLAGKVVVVDEAHAVDPYMQVLLEQLLRWL GTLDVPVVLLSATLHHSIANSLVKAYLEGARGRRWNRSEP QPVSEVSYPGWLHVDARIGKVTRSSDVDPLPIATTPRKPL EVRLVDVPVKEGALNRSTVLAKELTPLVKQGGCAAIICTT VAEAQGVYDLLSQWFATLGEDAPDLYLLHSRFPNRQRTEI TATIVDLFGKEGAQSGRRPTRGAVLVATQVVEQSLDLDVD LMISDLAPVSLLLQRAGRCWRHEHLGIINRPQWAKQPELV VLTPEQNAPWFPRSWTSVYPLALLQRTYTLLRRRNGAPVQ IPEDVQQLVDDVYDDDSLAEDLEADMERMGEELAQRGLAR NAVIPDPDDAEDNLNGLTEFSVLATRFGAGSVRVLCYYVD TAGNRWLDPECTVEFPEQGTGREGRFTMADCRDLVARTIP VRMGPWASQLTEDNHPPEAWRESFYLRDLVLIPQRVTDEG AVLPTETGGREWLLDPCKGLIF Description Functional site 1) chain C residue 84 type sequence D description BINDING SITE FOR RESIDUE FE C 1001 source : AC4 2) chain C residue 115 type sequence H description BINDING SITE FOR RESIDUE FE C 1001 source : AC4 3) chain C residue 149 type sequence H description BINDING SITE FOR RESIDUE FE C 1001 source : AC4 4) chain C residue 150 type sequence H description BINDING SITE FOR RESIDUE FE C 1001 source : AC4 5) chain C residue 37 type sequence H description BINDING SITE FOR RESIDUE FE C 1002 source : AC5 6) chain C residue 83 type sequence H description BINDING SITE FOR RESIDUE FE C 1002 source : AC5 7) chain C residue 84 type sequence D description BINDING SITE FOR RESIDUE FE C 1002 source : AC5 8) chain C residue 215 type sequence D description BINDING SITE FOR RESIDUE FE C 1002 source : AC5 9) chain C residue 277 type sequence L description BINDING SITE FOR RESIDUE ADP C 1003 source : AC6 10) chain C residue 279 type sequence K description BINDING SITE FOR RESIDUE ADP C 1003 source : AC6 11) chain C residue 281 type sequence N description BINDING SITE FOR RESIDUE ADP C 1003 source : AC6 12) chain C residue 284 type sequence Q description BINDING SITE FOR RESIDUE ADP C 1003 source : AC6 13) chain C residue 307 type sequence M description BINDING SITE FOR RESIDUE ADP C 1003 source : AC6 14) chain C residue 308 type sequence G description BINDING SITE FOR RESIDUE ADP C 1003 source : AC6 15) chain C residue 309 type sequence E description BINDING SITE FOR RESIDUE ADP C 1003 source : AC6 16) chain C residue 310 type sequence G description BINDING SITE FOR RESIDUE ADP C 1003 source : AC6 17) chain C residue 313 type sequence E description BINDING SITE FOR RESIDUE ADP C 1003 source : AC6 18) chain C residue 692 type sequence R description BINDING SITE FOR RESIDUE ADP C 1003 source : AC6

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