eF-site ID 4qo8-ABCD PDB Code 4qo8 Chain A, B, C, D click to enlarge Title Lactate Dehydrogenase A in complex with substituted 3-Hydroxy-2-mercaptocyclohex-2-enone compound 104 Classification oxidoreductase/oxidoreductase inhibitor Compound L-lactate dehydrogenase A chain Source Homo sapiens (Human) (LDHA_HUMAN) Sequence A:  ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILM KDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGK DYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFII PNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGS GCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVW SGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEV IKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLY GIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSAD TLWGIQKELQF B:  ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILM KDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGK DYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFII PNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGS GCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVW SGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEV IKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLY GIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSAD TLWGIQKELQF C:  ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILM KDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGK DYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFII PNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGS GCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVW SGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEV IKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLY GIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSAD TLWGIQKELQF D:  ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILM KDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGK DYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFII PNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGS GCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVW SGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEV IKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLY GIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSAD TLWGIQKELQF Description Functional site 1) chain A residue 28 type sequence G description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 2) chain A residue 29 type sequence A description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 3) chain A residue 30 type sequence V description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 4) chain A residue 51 type sequence D description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 5) chain A residue 52 type sequence V description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 6) chain A residue 53 type sequence I description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 7) chain A residue 94 type sequence T description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 8) chain A residue 95 type sequence A description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 9) chain A residue 96 type sequence G description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 10) chain A residue 98 type sequence R description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 11) chain A residue 115 type sequence I description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 12) chain A residue 119 type sequence I description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 13) chain A residue 135 type sequence V description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 14) chain A residue 136 type sequence S description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 15) chain A residue 137 type sequence N description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 16) chain A residue 160 type sequence S description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 17) chain A residue 192 type sequence H description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 18) chain A residue 247 type sequence T description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 19) chain A residue 251 type sequence I description BINDING SITE FOR RESIDUE NAI A 801 source : AC1 20) chain A residue 147 type sequence W description BINDING SITE FOR RESIDUE EPE A 802 source : AC2 21) chain A residue 151 type sequence G description BINDING SITE FOR RESIDUE EPE A 802 source : AC2 22) chain A residue 152 type sequence F description BINDING SITE FOR RESIDUE EPE A 802 source : AC2 23) chain A residue 154 type sequence K description BINDING SITE FOR RESIDUE EPE A 802 source : AC2 24) chain A residue 170 type sequence R description BINDING SITE FOR RESIDUE SO4 A 803 source : AC3 25) chain A residue 185 type sequence H description BINDING SITE FOR RESIDUE SO4 A 803 source : AC3 26) chain C residue 185 type sequence H description BINDING SITE FOR RESIDUE SO4 A 803 source : AC3 27) chain A residue 137 type sequence N description BINDING SITE FOR RESIDUE 36U A 804 source : AC4 28) chain A residue 165 type sequence D description BINDING SITE FOR RESIDUE 36U A 804 source : AC4 29) chain A residue 168 type sequence R description BINDING SITE FOR RESIDUE 36U A 804 source : AC4 30) chain A residue 192 type sequence H description BINDING SITE FOR RESIDUE 36U A 804 source : AC4 31) chain A residue 193 type sequence G description BINDING SITE FOR RESIDUE 36U A 804 source : AC4 32) chain A residue 237 type sequence A description BINDING SITE FOR RESIDUE 36U A 804 source : AC4 33) chain A residue 238 type sequence Y description BINDING SITE FOR RESIDUE 36U A 804 source : AC4 34) chain A residue 241 type sequence I description BINDING SITE FOR RESIDUE 36U A 804 source : AC4 35) chain A residue 247 type sequence T description BINDING SITE FOR RESIDUE 36U A 804 source : AC4 36) chain B residue 28 type sequence G description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 37) chain B residue 29 type sequence A description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 38) chain B residue 30 type sequence V description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 39) chain B residue 51 type sequence D description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 40) chain B residue 52 type sequence V description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 41) chain B residue 53 type sequence I description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 42) chain B residue 56 type sequence K description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 43) chain B residue 94 type sequence T description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 44) chain B residue 95 type sequence A description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 45) chain B residue 96 type sequence G description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 46) chain B residue 97 type sequence A description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 47) chain B residue 98 type sequence R description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 48) chain B residue 99 type sequence Q description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 49) chain B residue 115 type sequence I description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 50) chain B residue 119 type sequence I description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 51) chain B residue 135 type sequence V description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 52) chain B residue 137 type sequence N description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 53) chain B residue 160 type sequence S description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 54) chain B residue 164 type sequence L description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 55) chain B residue 192 type sequence H description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 56) chain B residue 247 type sequence T description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 57) chain B residue 251 type sequence I description BINDING SITE FOR RESIDUE NAI B 801 source : AC5 58) chain A residue 283 type sequence K description BINDING SITE FOR RESIDUE EPE B 802 source : AC6 59) chain B residue 147 type sequence W description BINDING SITE FOR RESIDUE EPE B 802 source : AC6 60) chain B residue 151 type sequence G description BINDING SITE FOR RESIDUE EPE B 802 source : AC6 61) chain B residue 153 type sequence P description BINDING SITE FOR RESIDUE EPE B 802 source : AC6 62) chain B residue 154 type sequence K description BINDING SITE FOR RESIDUE EPE B 802 source : AC6 63) chain B residue 99 type sequence Q description BINDING SITE FOR RESIDUE LAC B 803 source : AC7 64) chain B residue 105 type sequence R description BINDING SITE FOR RESIDUE LAC B 803 source : AC7 65) chain B residue 137 type sequence N description BINDING SITE FOR RESIDUE LAC B 803 source : AC7 66) chain B residue 168 type sequence R description BINDING SITE FOR RESIDUE LAC B 803 source : AC7 67) chain B residue 192 type sequence H description BINDING SITE FOR RESIDUE LAC B 803 source : AC7 68) chain B residue 237 type sequence A description BINDING SITE FOR RESIDUE LAC B 803 source : AC7 69) chain B residue 247 type sequence T description BINDING SITE FOR RESIDUE LAC B 803 source : AC7 70) chain B residue 170 type sequence R description BINDING SITE FOR RESIDUE SO4 B 804 source : AC8 71) chain B residue 185 type sequence H description BINDING SITE FOR RESIDUE SO4 B 804 source : AC8 72) chain D residue 185 type sequence H description BINDING SITE FOR RESIDUE SO4 B 804 source : AC8 73) chain C residue 28 type sequence G description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 74) chain C residue 29 type sequence A description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 75) chain C residue 30 type sequence V description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 76) chain C residue 51 type sequence D description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 77) chain C residue 52 type sequence V description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 78) chain C residue 53 type sequence I description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 79) chain C residue 94 type sequence T description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 80) chain C residue 95 type sequence A description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 81) chain C residue 96 type sequence G description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 82) chain C residue 115 type sequence I description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 83) chain C residue 135 type sequence V description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 84) chain C residue 136 type sequence S description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 85) chain C residue 137 type sequence N description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 86) chain C residue 192 type sequence H description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 87) chain C residue 247 type sequence T description BINDING SITE FOR RESIDUE NAI C 801 source : AC9 88) chain C residue 147 type sequence W description BINDING SITE FOR RESIDUE EPE C 802 source : BC1 89) chain C residue 151 type sequence G description BINDING SITE FOR RESIDUE EPE C 802 source : BC1 90) chain C residue 152 type sequence F description BINDING SITE FOR RESIDUE EPE C 802 source : BC1 91) chain C residue 153 type sequence P description BINDING SITE FOR RESIDUE EPE C 802 source : BC1 92) chain C residue 154 type sequence K description BINDING SITE FOR RESIDUE EPE C 802 source : BC1 93) chain A residue 182 type sequence L description BINDING SITE FOR RESIDUE SO4 C 803 source : BC2 94) chain A residue 185 type sequence H description BINDING SITE FOR RESIDUE SO4 C 803 source : BC2 95) chain C residue 170 type sequence R description BINDING SITE FOR RESIDUE SO4 C 803 source : BC2 96) chain C residue 185 type sequence H description BINDING SITE FOR RESIDUE SO4 C 803 source : BC2 97) chain C residue 137 type sequence N description BINDING SITE FOR RESIDUE 36U C 804 source : BC3 98) chain C residue 165 type sequence D description BINDING SITE FOR RESIDUE 36U C 804 source : BC3 99) chain C residue 168 type sequence R description BINDING SITE FOR RESIDUE 36U C 804 source : BC3 100) chain C residue 192 type sequence H description BINDING SITE FOR RESIDUE 36U C 804 source : BC3 101) chain C residue 193 type sequence G description BINDING SITE FOR RESIDUE 36U C 804 source : BC3 102) chain C residue 237 type sequence A description BINDING SITE FOR RESIDUE 36U C 804 source : BC3 103) chain C residue 238 type sequence Y description BINDING SITE FOR RESIDUE 36U C 804 source : BC3 104) chain C residue 101 type sequence E description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 105) chain D residue 28 type sequence G description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 106) chain D residue 29 type sequence A description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 107) chain D residue 30 type sequence V description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 108) chain D residue 51 type sequence D description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 109) chain D residue 52 type sequence V description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 110) chain D residue 53 type sequence I description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 111) chain D residue 94 type sequence T description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 112) chain D residue 95 type sequence A description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 113) chain D residue 115 type sequence I description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 114) chain D residue 119 type sequence I description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 115) chain D residue 135 type sequence V description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 116) chain D residue 137 type sequence N description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 117) chain D residue 160 type sequence S description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 118) chain D residue 192 type sequence H description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 119) chain D residue 247 type sequence T description BINDING SITE FOR RESIDUE NAI D 801 source : BC4 120) chain B residue 185 type sequence H description BINDING SITE FOR RESIDUE SO4 D 802 source : BC5 121) chain D residue 170 type sequence R description BINDING SITE FOR RESIDUE SO4 D 802 source : BC5 122) chain D residue 185 type sequence H description BINDING SITE FOR RESIDUE SO4 D 802 source : BC5 123) chain D residue 137 type sequence N description BINDING SITE FOR RESIDUE 36U D 803 source : BC6 124) chain D residue 165 type sequence D description BINDING SITE FOR RESIDUE 36U D 803 source : BC6 125) chain D residue 168 type sequence R description BINDING SITE FOR RESIDUE 36U D 803 source : BC6 126) chain D residue 192 type sequence H description BINDING SITE FOR RESIDUE 36U D 803 source : BC6 127) chain D residue 193 type sequence G description BINDING SITE FOR RESIDUE 36U D 803 source : BC6 128) chain D residue 237 type sequence A description BINDING SITE FOR RESIDUE 36U D 803 source : BC6 129) chain D residue 238 type sequence Y description BINDING SITE FOR RESIDUE 36U D 803 source : BC6 130) chain D residue 241 type sequence I description BINDING SITE FOR RESIDUE 36U D 803 source : BC6 131) chain D residue 247 type sequence T description BINDING SITE FOR RESIDUE 36U D 803 source : BC6 132) chain A residue 192 type ACT_SITE sequence H description Proton acceptor source Swiss-Prot : SWS_FT_FI1 133) chain B residue 192 type ACT_SITE sequence H description Proton acceptor source Swiss-Prot : SWS_FT_FI1 134) chain C residue 192 type ACT_SITE sequence H description Proton acceptor source Swiss-Prot : SWS_FT_FI1 135) chain D residue 192 type ACT_SITE sequence H description Proton acceptor source Swiss-Prot : SWS_FT_FI1 136) chain A residue 223 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 137) chain D residue 223 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 138) chain D residue 231 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 139) chain D residue 242 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 140) chain A residue 231 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 141) chain A residue 242 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 142) chain B residue 223 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 143) chain B residue 231 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 144) chain B residue 242 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 145) chain C residue 223 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 146) chain C residue 231 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 147) chain C residue 242 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI10 148) chain A residue 238 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI11 149) chain B residue 238 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI11 150) chain C residue 238 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI11 151) chain D residue 238 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI11 152) chain A residue 28 type BINDING sequence G description BINDING => ECO:0000269|PubMed:11276087 source Swiss-Prot : SWS_FT_FI2 153) chain A residue 98 type BINDING sequence R description BINDING => ECO:0000269|PubMed:11276087 source Swiss-Prot : SWS_FT_FI2 154) chain B residue 28 type BINDING sequence G description BINDING => ECO:0000269|PubMed:11276087 source Swiss-Prot : SWS_FT_FI2 155) chain B residue 98 type BINDING sequence R description BINDING => ECO:0000269|PubMed:11276087 source Swiss-Prot : SWS_FT_FI2 156) chain C residue 28 type BINDING sequence G description BINDING => ECO:0000269|PubMed:11276087 source Swiss-Prot : SWS_FT_FI2 157) chain C residue 98 type BINDING sequence R description BINDING => ECO:0000269|PubMed:11276087 source Swiss-Prot : SWS_FT_FI2 158) chain D residue 28 type BINDING sequence G description BINDING => ECO:0000269|PubMed:11276087 source Swiss-Prot : SWS_FT_FI2 159) chain D residue 98 type BINDING sequence R description BINDING => ECO:0000269|PubMed:11276087 source Swiss-Prot : SWS_FT_FI2 160) chain A residue 105 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 161) chain C residue 137 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI3 162) chain C residue 168 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 163) chain C residue 247 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI3 164) chain D residue 105 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 165) chain D residue 137 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI3 166) chain D residue 168 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 167) chain D residue 247 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI3 168) chain A residue 137 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI3 169) chain A residue 168 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 170) chain A residue 247 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI3 171) chain B residue 105 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 172) chain B residue 137 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI3 173) chain B residue 168 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 174) chain B residue 247 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI3 175) chain C residue 105 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 176) chain A residue 1 type MOD_RES sequence A description N-acetylalanine => ECO:0000269|Ref.10, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895 source Swiss-Prot : SWS_FT_FI4 177) chain B residue 1 type MOD_RES sequence A description N-acetylalanine => ECO:0000269|Ref.10, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895 source Swiss-Prot : SWS_FT_FI4 178) chain C residue 1 type MOD_RES sequence A description N-acetylalanine => ECO:0000269|Ref.10, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895 source Swiss-Prot : SWS_FT_FI4 179) chain D residue 1 type MOD_RES sequence A description N-acetylalanine => ECO:0000269|Ref.10, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895 source Swiss-Prot : SWS_FT_FI4 180) chain A residue 308 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:P04642 source Swiss-Prot : SWS_FT_FI12 181) chain A residue 321 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:P04642 source Swiss-Prot : SWS_FT_FI12 182) chain B residue 308 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:P04642 source Swiss-Prot : SWS_FT_FI12 183) chain B residue 321 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:P04642 source Swiss-Prot : SWS_FT_FI12 184) chain C residue 308 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:P04642 source Swiss-Prot : SWS_FT_FI12 185) chain C residue 321 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:P04642 source Swiss-Prot : SWS_FT_FI12 186) chain D residue 308 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:P04642 source Swiss-Prot : SWS_FT_FI12 187) chain D residue 321 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:P04642 source Swiss-Prot : SWS_FT_FI12 188) chain A residue 189-195 type prosite sequence LGEHGDS description L_LDH L-lactate dehydrogenase active site. LGEHGDS source prosite : PS00064 189) chain A residue 309 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI13 190) chain B residue 309 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI13 191) chain C residue 309 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI13 192) chain D residue 309 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI13 193) chain A residue 56 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI14 194) chain B residue 56 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI14 195) chain C residue 56 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI14 196) chain D residue 56 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI14 197) chain A residue 56 type MOD_RES sequence K description N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI9 198) chain B residue 56 type MOD_RES sequence K description N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI9 199) chain C residue 56 type MOD_RES sequence K description N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI9 200) chain D residue 56 type MOD_RES sequence K description N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI9 201) chain A residue 4 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 202) chain D residue 4 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 203) chain D residue 117 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 204) chain D residue 317 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 205) chain A residue 117 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 206) chain A residue 317 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 207) chain B residue 4 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 208) chain B residue 117 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 209) chain B residue 317 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 210) chain C residue 4 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 211) chain C residue 117 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 212) chain C residue 317 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P06151 source Swiss-Prot : SWS_FT_FI5 213) chain A residue 9 type MOD_RES sequence Y description Phosphotyrosine => ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI6 214) chain B residue 9 type MOD_RES sequence Y description Phosphotyrosine => ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI6 215) chain C residue 9 type MOD_RES sequence Y description Phosphotyrosine => ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI6 216) chain D residue 9 type MOD_RES sequence Y description Phosphotyrosine => ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI6 217) chain A residue 13 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 218) chain D residue 13 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 219) chain D residue 80 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 220) chain D residue 125 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 221) chain A residue 80 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 222) chain A residue 125 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 223) chain B residue 13 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 224) chain B residue 80 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 225) chain B residue 125 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 226) chain C residue 13 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 227) chain C residue 80 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 228) chain C residue 125 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI7 229) chain A residue 17 type MOD_RES sequence T description Phosphothreonine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI8 230) chain B residue 17 type MOD_RES sequence T description Phosphothreonine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI8 231) chain C residue 17 type MOD_RES sequence T description Phosphothreonine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI8 232) chain D residue 17 type MOD_RES sequence T description Phosphothreonine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI8

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