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|
eF-site ID
|
4qlt-Z |
|
PDB Code
|
4qlt |
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Chain
|
Z |
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click to enlarge
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Title
|
yCP in complex with tripeptidic epoxyketone inhibitor 2 (PR924) |
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Classification
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HYDROLASE/HYDROLASE INHIBITOR |
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Compound
|
Proteasome subunit alpha type-2 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
|
Z: |
QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYE
PKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHN
DKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKG
AVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQY
EPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGD
GLEILIVTKDGVRKEFYELKRD
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Description
|
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Functional site
|
|
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1)
|
chain |
Z |
| residue |
126 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE 39V Y 303
|
| source |
: BC2
|
|
|
2)
|
chain |
Z |
| residue |
192 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE MG Z 301
|
| source |
: BC3
|
|
|
3)
|
chain |
Z |
| residue |
195 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE MG Z 301
|
| source |
: BC3
|
|
|
4)
|
chain |
Z |
| residue |
196 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE MG Z 301
|
| source |
: BC3
|
|
|
5)
|
chain |
Z |
| residue |
198 |
| type |
|
| sequence |
V
|
| description |
BINDING SITE FOR RESIDUE MG Z 301
|
| source |
: BC3
|
|
|
|