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eF-site ID
|
4qfg-B |
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PDB Code
|
4qfg |
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Chain
|
B |
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click to enlarge
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Title
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Structure of AMPK in complex with STAUROSPORINE inhibitor and in the absence of a synthetic activator |
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Classification
|
signaling protein/inhibitor |
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Compound
|
5'-AMP-activated protein kinase catalytic subunit alpha-1 |
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Source
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Rattus norvegicus (Rat) (AAKG1_RAT) |
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Sequence
|
B: |
ARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRDQNNFVAIL
DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVK
KTDFEVFDALMVDSQKAPPILPPHLLQVILNKSCDPALLP
EPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKP
I
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Description
|
(1) |
5'-AMP-activated protein kinase catalytic subunit alpha-1 (E.C.2.7.11.1, 2.7.11.27, 2.7.11.31, 2.7.11.26), 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1
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Functional site
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|
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1)
|
chain |
B |
| residue |
83 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE SO4 A 605
|
| source |
: AC5
|
|
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2)
|
chain |
B |
| residue |
110 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE SO4 A 605
|
| source |
: AC5
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