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eF-site ID
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4q5e-C |
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PDB Code
|
4q5e |
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Chain
|
C |
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click to enlarge
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Title
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Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate |
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Classification
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UNKNOWN FUNCTION, PROTEIN BINDING |
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Compound
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Protein kinase OspG |
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Source
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Shigella sonnei (strain Ss046) (UB2L3_HUMAN) |
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Sequence
|
C: |
HMAASRRLMKELEEIRKSGMKNFRNIQVDEANLLTWQGLI
VPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNI
DEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
PLRADLAEEYSKDRKKFSKNAEEFTKKYGEKRPVD
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Description
|
(1) |
Protein kinase OspG (E.C.2.7.-.-), Polyubiquitin (E.C.6.3.2.19), Ubiquitin-conjugating enzyme E2 L3 (E.C.6.3.2.19)
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Functional site
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1)
|
chain |
C |
| residue |
86 |
| type |
catalytic |
| sequence |
C
|
| description |
438
|
| source |
MCSA : MCSA1
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2)
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chain |
C |
| residue |
86 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133
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| source |
Swiss-Prot : SWS_FT_FI1
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|
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3)
|
chain |
C |
| residue |
131 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
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| source |
Swiss-Prot : SWS_FT_FI2
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|
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4)
|
chain |
C |
| residue |
75-90 |
| type |
prosite |
| sequence |
YHPNIDEKGQVCLPVI
|
| description |
UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNIdek.GqVCLpvI
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| source |
prosite : PS00183
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