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eF-site ID
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4q4z-C |
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PDB Code
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4q4z |
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Chain
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C |
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click to enlarge
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Title
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Thermus thermophilus RNA polymerase de novo transcription initiation complex |
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Classification
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transcription/DNA |
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Compound
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DNA-directed RNA polymerase subunit alpha |
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Source
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ORGANISM_SCIENTIFIC: Thermus thermophilus; |
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Sequence
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C: |
MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRE
NVGIQAAFRETFPIEEGLVLDFLEYRLGEPPFPQDECREK
DLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGS
FIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLP
KRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQET
LARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGD
PPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLS
GRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDID
HLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDS
LTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRH
KRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEG
ANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYM
TATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSP
EEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQT
QAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKV
DGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVG
QRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFED
AIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDI
PHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESE
PTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRL
RRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNK
GVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQIL
ETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYF
GKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKEL
FLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMH
ARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAA
HTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFR
VLVKELQALALDVQTLDEKDNPVDIFEGLASK
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Description
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Functional site
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1)
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chain |
C |
| residue |
567 |
| type |
|
| sequence |
Q
|
| description |
BINDING SITE FOR RESIDUE ATP C 1201
|
| source |
: AC1
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2)
|
chain |
C |
| residue |
838 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE ATP C 1201
|
| source |
: AC1
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3)
|
chain |
C |
| residue |
999 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ATP C 1201
|
| source |
: AC1
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|
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4)
|
chain |
C |
| residue |
557 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE 2TM D 2006
|
| source |
: AC7
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5)
|
chain |
C |
| residue |
879 |
| type |
|
| sequence |
R
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| description |
BINDING SITE FOR RESIDUE 2TM D 2006
|
| source |
: AC7
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|
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6)
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chain |
C |
| residue |
836-848 |
| type |
prosite |
| sequence |
GDKLANRHGNKGV
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| description |
RNA_POL_BETA RNA polymerases beta chain signature. GdKLANrHGNKGV
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| source |
prosite : PS01166
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