eF-site ID 4q2g-AB PDB Code 4q2g Chain A, B click to enlarge Title CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S223C, inactive mutant) Classification TRANSFERASE Compound Phosphatidate cytidylyltransferase Source Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) (CDSA_THEMA) Sequence A:  TASVVAPFVVLCFVSYESLIGLVSAILILAGYELITLEMK ERDARFFYVILLALYPVLYGLVFEEPTQPLSILFITGVVF SLITDKDPSQVFKTVAAFSIALIYVTFFLSFFLPIYRDFG AANALLVLTSTWVFDSFAYFTGLKFGRTRISPRYSPRKSL EGVIGGFLGVVIYTFLYRLVVNDLLSVNVICFRTFLPFAA TVAIMDTFGDIFESALKRHYGVKDSGKTLPGHGGMLDRID GLLFVAPVCYIVFKILEGVVR B:  DDLKTRVITASVVAPFVVLCFVSYESLIGLVSAILILAGY ELITLEMKERDARFFYVILLALYPVLYGLVFEEPTQPLSI LFITGVVFSLITDKDPSQVFKTVAAFSIALIYVTFFLSFF LPIYRDFGAANALLVLTSTWVFDSFAYFTGLKFGRTRISP RYSPRKSLEGVIGGFLGVVIYTFLYRLVVNDLLSVNVICF RTFLPFAATVAIMDTFGDIFESALKRHYGVKDSGKTLPGH GGMLDRIDGLLFVAPVCYIVFKILEGVVR Description Functional site 1) chain A residue 37-57 type TRANSMEM sequence FVVLCFVSYESLIGLVSAILI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 2) chain B residue 75-95 type TRANSMEM sequence FFYVILLALYPVLYGLVFEEP description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 3) chain B residue 101-121 type TRANSMEM sequence ILFITGVVFSLITDKDPSQVF description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 4) chain B residue 124-144 type TRANSMEM sequence VAAFSIALIYVTFFLSFFLPI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 5) chain B residue 149-169 type TRANSMEM sequence GAANALLVLTSTWVFDSFAYF description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 6) chain B residue 190-210 type TRANSMEM sequence EGVIGGFLGVVIYTFLYRLVV description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 7) chain B residue 213-233 type TRANSMEM sequence LLSVNVICFRTFLPFAATVAI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 8) chain B residue 268-288 type TRANSMEM sequence IDGLLFVAPVCYIVFKILEGV description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 9) chain A residue 75-95 type TRANSMEM sequence FFYVILLALYPVLYGLVFEEP description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 10) chain A residue 101-121 type TRANSMEM sequence ILFITGVVFSLITDKDPSQVF description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 11) chain A residue 124-144 type TRANSMEM sequence VAAFSIALIYVTFFLSFFLPI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 12) chain A residue 149-169 type TRANSMEM sequence GAANALLVLTSTWVFDSFAYF description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 13) chain A residue 190-210 type TRANSMEM sequence EGVIGGFLGVVIYTFLYRLVV description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 14) chain A residue 213-233 type TRANSMEM sequence LLSVNVICFRTFLPFAATVAI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 15) chain A residue 268-288 type TRANSMEM sequence IDGLLFVAPVCYIVFKILEGV description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 16) chain B residue 37-57 type TRANSMEM sequence FVVLCFVSYESLIGLVSAILI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 17) chain A residue 243-269 type prosite sequence SALKRHYGVKDSGKTLPGHGGMLDRID description CDS Phosphatidate cytidylyltransferase signature. SaLKRhygvKDsGktLPgHGGMlDRID source prosite : PS01315

Display surface Download Links