|
|
eF-site ID
|
4q2g-A |
|
PDB Code
|
4q2g |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S223C, inactive mutant) |
|
Classification
|
TRANSFERASE |
|
Compound
|
Phosphatidate cytidylyltransferase |
|
Source
|
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) (CDSA_THEMA) |
|
|
Sequence
|
A: |
TASVVAPFVVLCFVSYESLIGLVSAILILAGYELITLEMK
ERDARFFYVILLALYPVLYGLVFEEPTQPLSILFITGVVF
SLITDKDPSQVFKTVAAFSIALIYVTFFLSFFLPIYRDFG
AANALLVLTSTWVFDSFAYFTGLKFGRTRISPRYSPRKSL
EGVIGGFLGVVIYTFLYRLVVNDLLSVNVICFRTFLPFAA
TVAIMDTFGDIFESALKRHYGVKDSGKTLPGHGGMLDRID
GLLFVAPVCYIVFKILEGVVR
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
37-57 |
| type |
TRANSMEM |
| sequence |
FVVLCFVSYESLIGLVSAILI
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
75-95 |
| type |
TRANSMEM |
| sequence |
FFYVILLALYPVLYGLVFEEP
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
101-121 |
| type |
TRANSMEM |
| sequence |
ILFITGVVFSLITDKDPSQVF
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
124-144 |
| type |
TRANSMEM |
| sequence |
VAAFSIALIYVTFFLSFFLPI
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
149-169 |
| type |
TRANSMEM |
| sequence |
GAANALLVLTSTWVFDSFAYF
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
190-210 |
| type |
TRANSMEM |
| sequence |
EGVIGGFLGVVIYTFLYRLVV
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
213-233 |
| type |
TRANSMEM |
| sequence |
LLSVNVICFRTFLPFAATVAI
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
A |
| residue |
268-288 |
| type |
TRANSMEM |
| sequence |
IDGLLFVAPVCYIVFKILEGV
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
A |
| residue |
243-269 |
| type |
prosite |
| sequence |
SALKRHYGVKDSGKTLPGHGGMLDRID
|
| description |
CDS Phosphatidate cytidylyltransferase signature. SaLKRhygvKDsGktLPgHGGMlDRID
|
| source |
prosite : PS01315
|
|
|
|