eF-site ID 4pv2-ABCD PDB Code 4pv2 Chain A, B, C, D click to enlarge Title Crystal structure of potassium-dependent plant-type L-asparaginase from Phaseolus vulgaris in complex with K+ and Na+ cations Classification HYDROLASE Compound L-ASPARAGINASE ALPHA SUBUNIT Source Phaseolus vulgaris (Kidney bean) (French bean) (V7CU13_PHAVU) Sequence A:  GGWAIAVHGGAGVDPTLPLERQEEAKQLLTRCLNLGISAL NSNVPAIDVVELVVRELETDPLFNSGRGSALTEKGTVEME ASIMDGPKRRCGAVSGLTTVKNPISLARLVMDKSPHSYIA FSGAEDFARQQGVEVVDNEYFVTPDNVGMLKLAKE B:  TVGCVVVDREGRCAAATSTGGLMNKMTGRIGDSPLIGAGT YACDVCGVSCTGEGEAIIRGTLAREVAAVMEYKGLKLHQA VDFVIKHRLDEGKAGLIAVSNTGEVACGFNCNGMFRACAT EDGFMEVAIWD C:  GGWAIAVHGGAGVDPTLPLERQEEAKQLLTRCLNLGISAL NSNVPAIDVVELVVRELETDPLFNSGRGSALTEKGTVEME ASIMDGPKRRCGAVSGLTTVKNPISLARLVMDKSPHSYIA FSGAEDFARQQGVEVVDNEYFVTPDNVGMLKLAKEANT D:  TVGCVVVDREGRCAAATSTGGLMNKMTGRIGDSPLIGAGT YACDVCGVSCTGEGEAIIRGTLAREVAAVMEYKGLKLHQA VDFVIKHRLDEGKAGLIAVSNTGEVACGFNCNGMFRACAT EDGFMEVAIWD Description Functional site 1) chain A residue 58 type sequence L description BINDING SITE FOR RESIDUE NA A 201 source : AC1 2) chain A residue 59 type sequence E description BINDING SITE FOR RESIDUE NA A 201 source : AC1 3) chain A residue 61 type sequence D description BINDING SITE FOR RESIDUE NA A 201 source : AC1 4) chain A residue 64 type sequence F description BINDING SITE FOR RESIDUE NA A 201 source : AC1 5) chain A residue 66 type sequence S description BINDING SITE FOR RESIDUE NA A 201 source : AC1 6) chain A residue 68 type sequence R description BINDING SITE FOR RESIDUE NA A 201 source : AC1 7) chain A residue 111 type sequence V description BINDING SITE FOR RESIDUE NA A 202 source : AC2 8) chain A residue 112 type sequence M description BINDING SITE FOR RESIDUE NA A 202 source : AC2 9) chain A residue 115 type sequence S description BINDING SITE FOR RESIDUE NA A 202 source : AC2 10) chain A residue 117 type sequence H description BINDING SITE FOR RESIDUE NA A 202 source : AC2 11) chain A residue 58 type sequence L description BINDING SITE FOR RESIDUE K A 203 source : AC3 12) chain A residue 61 type sequence D description BINDING SITE FOR RESIDUE K A 203 source : AC3 13) chain A residue 64 type sequence F description BINDING SITE FOR RESIDUE K A 203 source : AC3 14) chain A residue 66 type sequence S description BINDING SITE FOR RESIDUE K A 203 source : AC3 15) chain A residue 68 type sequence R description BINDING SITE FOR RESIDUE K A 203 source : AC3 16) chain A residue 92 type sequence C description BINDING SITE FOR RESIDUE K A 204 source : AC4 17) chain A residue 111 type sequence V description BINDING SITE FOR RESIDUE K A 204 source : AC4 18) chain A residue 112 type sequence M description BINDING SITE FOR RESIDUE K A 204 source : AC4 19) chain A residue 115 type sequence S description BINDING SITE FOR RESIDUE K A 204 source : AC4 20) chain A residue 117 type sequence H description BINDING SITE FOR RESIDUE K A 204 source : AC4 21) chain A residue 118 type sequence S description BINDING SITE FOR RESIDUE K A 204 source : AC4 22) chain A residue 88 type sequence P description BINDING SITE FOR RESIDUE NO3 A 205 source : AC5 23) chain A residue 89 type sequence K description BINDING SITE FOR RESIDUE NO3 A 205 source : AC5 24) chain A residue 90 type sequence R description BINDING SITE FOR RESIDUE NO3 A 205 source : AC5 25) chain D residue 254 type sequence R description BINDING SITE FOR RESIDUE NO3 A 205 source : AC5 26) chain D residue 285 type sequence D description BINDING SITE FOR RESIDUE NO3 A 205 source : AC5 27) chain A residue 140 type sequence E description BINDING SITE FOR RESIDUE NO3 A 206 source : AC6 28) chain A residue 143 type sequence V description BINDING SITE FOR RESIDUE NO3 A 206 source : AC6 29) chain A residue 68 type sequence R description BINDING SITE FOR RESIDUE NO3 A 207 source : AC7 30) chain A residue 141 type sequence Y description BINDING SITE FOR RESIDUE NO3 A 207 source : AC7 31) chain A residue 143 type sequence V description BINDING SITE FOR RESIDUE NO3 A 207 source : AC7 32) chain A residue 144 type sequence T description BINDING SITE FOR RESIDUE NO3 A 207 source : AC7 33) chain C residue 32 type sequence R description BINDING SITE FOR RESIDUE NO3 A 207 source : AC7 34) chain A residue 90 type sequence R description BINDING SITE FOR RESIDUE NO3 B 401 source : AC8 35) chain B residue 238 type sequence C description BINDING SITE FOR RESIDUE NO3 B 401 source : AC8 36) chain B residue 239 type sequence D description BINDING SITE FOR RESIDUE NO3 B 401 source : AC8 37) chain B residue 221 type sequence M description BINDING SITE FOR RESIDUE NO3 B 402 source : AC9 38) chain B residue 224 type sequence R description BINDING SITE FOR RESIDUE NO3 B 402 source : AC9 39) chain C residue 114 type sequence K description BINDING SITE FOR RESIDUE NO3 B 402 source : AC9 40) chain C residue 115 type sequence S description BINDING SITE FOR RESIDUE NO3 B 402 source : AC9 41) chain C residue 116 type sequence P description BINDING SITE FOR RESIDUE NO3 B 402 source : AC9 42) chain C residue 117 type sequence H description BINDING SITE FOR RESIDUE NO3 B 402 source : AC9 43) chain C residue 128 type sequence F description BINDING SITE FOR RESIDUE NO3 B 402 source : AC9 44) chain C residue 131 type sequence Q description BINDING SITE FOR RESIDUE NO3 B 402 source : AC9 45) chain A residue 27 type sequence K description BINDING SITE FOR RESIDUE NO3 B 403 source : BC1 46) chain B residue 323 type sequence A description BINDING SITE FOR RESIDUE NO3 B 403 source : BC1 47) chain B residue 324 type sequence I description BINDING SITE FOR RESIDUE NO3 B 403 source : BC1 48) chain B residue 325 type sequence W description BINDING SITE FOR RESIDUE NO3 B 403 source : BC1 49) chain C residue 58 type sequence L description BINDING SITE FOR RESIDUE NA C 201 source : BC2 50) chain C residue 59 type sequence E description BINDING SITE FOR RESIDUE NA C 201 source : BC2 51) chain C residue 61 type sequence D description BINDING SITE FOR RESIDUE NA C 201 source : BC2 52) chain C residue 66 type sequence S description BINDING SITE FOR RESIDUE NA C 201 source : BC2 53) chain C residue 68 type sequence R description BINDING SITE FOR RESIDUE NA C 201 source : BC2 54) chain C residue 111 type sequence V description BINDING SITE FOR RESIDUE NA C 202 source : BC3 55) chain C residue 112 type sequence M description BINDING SITE FOR RESIDUE NA C 202 source : BC3 56) chain C residue 115 type sequence S description BINDING SITE FOR RESIDUE NA C 202 source : BC3 57) chain C residue 117 type sequence H description BINDING SITE FOR RESIDUE NA C 202 source : BC3 58) chain C residue 58 type sequence L description BINDING SITE FOR RESIDUE K C 203 source : BC4 59) chain C residue 61 type sequence D description BINDING SITE FOR RESIDUE K C 203 source : BC4 60) chain C residue 64 type sequence F description BINDING SITE FOR RESIDUE K C 203 source : BC4 61) chain C residue 66 type sequence S description BINDING SITE FOR RESIDUE K C 203 source : BC4 62) chain C residue 112 type sequence M description BINDING SITE FOR RESIDUE K C 204 source : BC5 63) chain C residue 115 type sequence S description BINDING SITE FOR RESIDUE K C 204 source : BC5 64) chain C residue 18 type sequence L description BINDING SITE FOR RESIDUE NO3 C 205 source : BC6 65) chain C residue 22 type sequence R description BINDING SITE FOR RESIDUE NO3 C 205 source : BC6 66) chain D residue 310 type sequence F description BINDING SITE FOR RESIDUE NO3 C 205 source : BC6 67) chain A residue 122 type sequence F description BINDING SITE FOR RESIDUE NO3 C 206 source : BC7 68) chain A residue 123 type sequence S description BINDING SITE FOR RESIDUE NO3 C 206 source : BC7 69) chain C residue 122 type sequence F description BINDING SITE FOR RESIDUE NO3 C 206 source : BC7 70) chain C residue 123 type sequence S description BINDING SITE FOR RESIDUE NO3 C 206 source : BC7 71) chain A residue 141 type sequence Y description BINDING SITE FOR RESIDUE NO3 C 207 source : BC8 72) chain C residue 32 type sequence R description BINDING SITE FOR RESIDUE NO3 C 207 source : BC8 73) chain C residue 35 type sequence N description BINDING SITE FOR RESIDUE NO3 C 207 source : BC8 74) chain A residue 56 type sequence R description BINDING SITE FOR RESIDUE NO3 C 208 source : BC9 75) chain A residue 135 type sequence E description BINDING SITE FOR RESIDUE NO3 C 208 source : BC9 76) chain C residue 56 type sequence R description BINDING SITE FOR RESIDUE NO3 C 208 source : BC9 77) chain C residue 135 type sequence E description BINDING SITE FOR RESIDUE NO3 C 208 source : BC9 78) chain A residue 35 type sequence N description BINDING SITE FOR RESIDUE NO3 C 209 source : CC1 79) chain B residue 221 type sequence M description BINDING SITE FOR RESIDUE NO3 C 210 source : CC2 80) chain B residue 224 type sequence R description BINDING SITE FOR RESIDUE NO3 C 210 source : CC2 81) chain C residue 124 type sequence G description BINDING SITE FOR RESIDUE NO3 C 210 source : CC2 82) chain C residue 127 type sequence D description BINDING SITE FOR RESIDUE NO3 C 210 source : CC2 83) chain C residue 128 type sequence F description BINDING SITE FOR RESIDUE NO3 C 210 source : CC2 84) chain C residue 131 type sequence Q description BINDING SITE FOR RESIDUE NO3 C 210 source : CC2 85) chain A residue 36 type sequence L description BINDING SITE FOR RESIDUE NO3 C 211 source : CC3 86) chain A residue 39 type sequence S description BINDING SITE FOR RESIDUE NO3 C 211 source : CC3 87) chain C residue 137 type sequence V description BINDING SITE FOR RESIDUE NO3 C 211 source : CC3 88) chain C residue 138 type sequence D description BINDING SITE FOR RESIDUE NO3 C 211 source : CC3 89) chain D residue 265 type sequence M description BINDING SITE FOR RESIDUE NO3 D 401 source : CC4 90) chain D residue 271 type sequence K description BINDING SITE FOR RESIDUE NO3 D 401 source : CC4 91) chain D residue 272 type sequence L description BINDING SITE FOR RESIDUE NO3 D 401 source : CC4 92) chain D residue 295 type sequence S description BINDING SITE FOR RESIDUE NO3 D 401 source : CC4 93) chain D residue 297 type sequence T description BINDING SITE FOR RESIDUE NO3 D 401 source : CC4 94) chain D residue 299 type sequence E description BINDING SITE FOR RESIDUE NO3 D 401 source : CC4 95) chain C residue 27 type sequence K description BINDING SITE FOR RESIDUE NO3 D 402 source : CC5 96) chain D residue 324 type sequence I description BINDING SITE FOR RESIDUE NO3 D 402 source : CC5 97) chain D residue 325 type sequence W description BINDING SITE FOR RESIDUE NO3 D 402 source : CC5 98) chain C residue 90 type sequence R description BINDING SITE FOR RESIDUE NO3 D 403 source : CC6 99) chain D residue 238 type sequence C description BINDING SITE FOR RESIDUE NO3 D 403 source : CC6 100) chain D residue 239 type sequence D description BINDING SITE FOR RESIDUE NO3 D 403 source : CC6 101) chain D residue 301 type sequence A description BINDING SITE FOR RESIDUE NO3 D 404 source : CC7 102) chain D residue 302 type sequence C description BINDING SITE FOR RESIDUE NO3 D 404 source : CC7 103) chain A residue 115 type sequence S description BINDING SITE FOR RESIDUE NO3 D 405 source : CC8 104) chain A residue 116 type sequence P description BINDING SITE FOR RESIDUE NO3 D 405 source : CC8 105) chain A residue 117 type sequence H description BINDING SITE FOR RESIDUE NO3 D 405 source : CC8 106) chain A residue 128 type sequence F description BINDING SITE FOR RESIDUE NO3 D 405 source : CC8 107) chain D residue 221 type sequence M description BINDING SITE FOR RESIDUE NO3 D 405 source : CC8 108) chain D residue 224 type sequence R description BINDING SITE FOR RESIDUE NO3 D 405 source : CC8 109) chain C residue 20 type sequence L description BINDING SITE FOR RESIDUE NO3 D 406 source : CC9 110) chain C residue 24 type sequence E description BINDING SITE FOR RESIDUE NO3 D 406 source : CC9 111) chain D residue 268 type sequence K description BINDING SITE FOR RESIDUE NO3 D 406 source : CC9 112) chain D residue 270 type sequence L description BINDING SITE FOR RESIDUE NO3 D 406 source : CC9 113) chain D residue 301 type sequence A description BINDING SITE FOR RESIDUE NO3 D 407 source : DC1 114) chain D residue 302 type sequence C description BINDING SITE FOR RESIDUE NO3 D 407 source : DC1 115) chain D residue 313 type sequence C description BINDING SITE FOR RESIDUE NO3 D 407 source : DC1 116) chain D residue 319 type sequence F description BINDING SITE FOR RESIDUE NO3 D 407 source : DC1 117) chain D residue 321 type sequence E description BINDING SITE FOR RESIDUE NO3 D 407 source : DC1 118) chain B residue 266 type sequence E description BINDING SITE FOR RESIDUE NO3 D 408 source : DC2 119) chain D residue 268 type sequence K description BINDING SITE FOR RESIDUE NO3 D 408 source : DC2

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