|
|
eF-site ID
|
4pr9-D |
|
PDB Code
|
4pr9 |
|
Chain
|
D |
|
click to enlarge
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|
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Title
|
Human Vinculin (residues 891-1066) in complex with PIP |
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Classification
|
CELL ADHESION, STRUCTURAL PROTEIN |
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Compound
|
Vinculin |
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Source
|
Homo sapiens (Human) (VINC_HUMAN) |
|
|
Sequence
|
D: |
GEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLM
AEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAK
QCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTN
ISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRT
DAGFTLRWVAKTPWYQ
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
D |
| residue |
915 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE PIO B 1101
|
| source |
: AC2
|
|
|
2)
|
chain |
D |
| residue |
944 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE PIO E 1101
|
| source |
: AC5
|
|
|
3)
|
chain |
D |
| residue |
945 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE PIO E 1101
|
| source |
: AC5
|
|
|
4)
|
chain |
D |
| residue |
1004 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE PIO E 1101
|
| source |
: AC5
|
|
|
5)
|
chain |
D |
| residue |
1065 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine; by SRC-type Tyr-kinases => ECO:0000269|PubMed:15229287
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|