eF-site ID 4pr9-ABCDEF PDB Code 4pr9 Chain A, B, C, D, E, F click to enlarge Title Human Vinculin (residues 891-1066) in complex with PIP Classification CELL ADHESION, STRUCTURAL PROTEIN Compound Vinculin Source Homo sapiens (Human) (VINC_HUMAN) Sequence A:  GEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLM AEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAK QCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTN ISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRT DAGFTLRWVAKTPWY B:  GEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLM AEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAK QCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTN ISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRT DAGFTLRWVAKTPWYQ C:  GEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLM AEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAK QCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTN ISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRT DAGFTLRWVAKTPW D:  GEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLM AEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAK QCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTN ISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRT DAGFTLRWVAKTPWYQ E:  VINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLMAE MSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQC TDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNIS DEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDA GFTLRWVAKTPW F:  INQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLMAEM SRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCT DKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISD EESEQATEMLVHNAQNLMQSVKETVREAEAAAGFTLRWPW Description Functional site 1) chain A residue 914 type sequence S description BINDING SITE FOR RESIDUE PIO A 1101 source : AC1 2) chain A residue 915 type sequence K description BINDING SITE FOR RESIDUE PIO A 1101 source : AC1 3) chain A residue 1061 type sequence K description BINDING SITE FOR RESIDUE PIO A 1101 source : AC1 4) chain B residue 915 type sequence K description BINDING SITE FOR RESIDUE PIO A 1101 source : AC1 5) chain B residue 1061 type sequence K description BINDING SITE FOR RESIDUE PIO A 1101 source : AC1 6) chain B residue 944 type sequence K description BINDING SITE FOR RESIDUE PIO B 1101 source : AC2 7) chain B residue 945 type sequence R description BINDING SITE FOR RESIDUE PIO B 1101 source : AC2 8) chain C residue 915 type sequence K description BINDING SITE FOR RESIDUE PIO B 1101 source : AC2 9) chain D residue 915 type sequence K description BINDING SITE FOR RESIDUE PIO B 1101 source : AC2 10) chain B residue 915 type sequence K description BINDING SITE FOR RESIDUE GOL B 1102 source : AC3 11) chain D residue 944 type sequence K description BINDING SITE FOR RESIDUE PIO E 1101 source : AC5 12) chain D residue 945 type sequence R description BINDING SITE FOR RESIDUE PIO E 1101 source : AC5 13) chain D residue 1004 type sequence T description BINDING SITE FOR RESIDUE PIO E 1101 source : AC5 14) chain E residue 913 type sequence S description BINDING SITE FOR RESIDUE PIO E 1101 source : AC5 15) chain E residue 914 type sequence S description BINDING SITE FOR RESIDUE PIO E 1101 source : AC5 16) chain E residue 915 type sequence K description BINDING SITE FOR RESIDUE PIO E 1101 source : AC5 17) chain E residue 1061 type sequence K description BINDING SITE FOR RESIDUE PIO E 1101 source : AC5 18) chain F residue 914 type sequence S description BINDING SITE FOR RESIDUE PIO E 1101 source : AC5 19) chain F residue 915 type sequence K description BINDING SITE FOR RESIDUE PIO E 1101 source : AC5 20) chain F residue 1057 type sequence R description BINDING SITE FOR RESIDUE PIO E 1101 source : AC5 21) chain A residue 1065 type MOD_RES sequence Y description Phosphotyrosine; by SRC-type Tyr-kinases => ECO:0000269|PubMed:15229287 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 1065 type MOD_RES sequence Y description Phosphotyrosine; by SRC-type Tyr-kinases => ECO:0000269|PubMed:15229287 source Swiss-Prot : SWS_FT_FI1 23) chain D residue 1065 type MOD_RES sequence Y description Phosphotyrosine; by SRC-type Tyr-kinases => ECO:0000269|PubMed:15229287 source Swiss-Prot : SWS_FT_FI1

Display surface Download Links