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eF-site ID
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4pd4-B |
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PDB Code
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4pd4 |
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Chain
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B |
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click to enlarge
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Title
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Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action |
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Classification
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OXIDOREDUCTASE/INHIBITOR |
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Compound
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Cytochrome b-c1 complex subunit 1, mitochondrial |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); |
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Sequence
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B: |
LTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNF
QNTNTRSALKLVRESELLGGTFKSTLDREYITLKATFLKD
DLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQ
CPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFA
DKVYTKENLEVSGENVVEADLKRFVDESLLSTLPAGKSLV
SKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVL
ANYLTSALSELSGLISSAKLDKFTDGGLFTLFVRDQDSAV
VSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVSSPI
ELNFDAVKDFKLGKFNYVAVGDVSNLPYLDEL
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Description
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Functional site
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1)
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chain |
B |
| residue |
37-59 |
| type |
prosite |
| sequence |
GGSRYATKDGVAHLLNRFNFQNT
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| description |
INSULINASE Insulinase family, zinc-binding region signature. Ggsryatkd.GvAHLLNRFnFqNT
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| source |
prosite : PS00143
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