eF-site ID 4ouf-AB PDB Code 4ouf Chain A, B click to enlarge Title Crystal Structure of CBP bromodomain Classification TRANSFERASE Compound CREB-binding protein Source Homo sapiens (Human) (CBP_HUMAN) Sequence A:  KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI PDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFN NAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSL B:  IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP DYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNN AWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQS Description Functional site 1) chain A residue 1109 type sequence L description BINDING SITE FOR RESIDUE PEG A 1201 source : AC1 2) chain A residue 1110 type sequence P description BINDING SITE FOR RESIDUE PEG A 1201 source : AC1 3) chain A residue 1173 type sequence R description BINDING SITE FOR RESIDUE PEG A 1201 source : AC1 4) chain B residue 1109 type sequence L description BINDING SITE FOR RESIDUE PEG A 1201 source : AC1 5) chain B residue 1110 type sequence P description BINDING SITE FOR RESIDUE PEG A 1201 source : AC1 6) chain A residue 1123 type sequence P description BINDING SITE FOR RESIDUE EDO A 1202 source : AC2 7) chain A residue 1124 type sequence D description BINDING SITE FOR RESIDUE EDO A 1202 source : AC2 8) chain A residue 1169 type sequence R description BINDING SITE FOR RESIDUE EDO A 1202 source : AC2 9) chain A residue 1172 type sequence S description BINDING SITE FOR RESIDUE EDO A 1202 source : AC2 10) chain A residue 1176 type sequence K description BINDING SITE FOR RESIDUE EDO A 1202 source : AC2 11) chain A residue 1114 type sequence P description BINDING SITE FOR RESIDUE EDO A 1203 source : AC3 12) chain A residue 1115 type sequence V description BINDING SITE FOR RESIDUE EDO A 1203 source : AC3 13) chain A residue 1116 type sequence D description BINDING SITE FOR RESIDUE EDO A 1203 source : AC3 14) chain A residue 1165 type sequence W description BINDING SITE FOR RESIDUE EDO A 1204 source : AC4 15) chain A residue 1175 type sequence Y description BINDING SITE FOR RESIDUE EDO A 1204 source : AC4 16) chain B residue 1110 type sequence P description BINDING SITE FOR RESIDUE EDO B 1201 source : AC5 17) chain B residue 1113 type sequence Q description BINDING SITE FOR RESIDUE EDO B 1201 source : AC5 18) chain B residue 1114 type sequence P description BINDING SITE FOR RESIDUE EDO B 1201 source : AC5 19) chain B residue 1115 type sequence V description BINDING SITE FOR RESIDUE EDO B 1201 source : AC5 20) chain B residue 1120 type sequence L description BINDING SITE FOR RESIDUE EDO B 1201 source : AC5 21) chain A residue 1108-1167 type prosite sequence SLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQY QEPWQYVDDVWLMFNNAWLY description BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY source prosite : PS00633

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