eF-site ID 4orc-A PDB Code 4orc Chain A click to enlarge Title Crystal structure of mammalian calcineurin Classification HYDROLASE/METAL BINDING PROTEIN Compound Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform Source Homo sapiens (Human) (CANB1_HUMAN) Sequence A:  PPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRV DVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEA PITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFK QECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLS PEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEA QDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK YENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTE MLVNVLSICSDDELVFSV Description Functional site 1) chain A residue 127 type sequence D description BINDING SITE FOR RESIDUE ZN A 601 source : AC1 2) chain A residue 159 type sequence N description BINDING SITE FOR RESIDUE ZN A 601 source : AC1 3) chain A residue 208 type sequence H description BINDING SITE FOR RESIDUE ZN A 601 source : AC1 4) chain A residue 290 type sequence H description BINDING SITE FOR RESIDUE ZN A 601 source : AC1 5) chain A residue 99 type sequence D description BINDING SITE FOR RESIDUE FE A 602 source : AC2 6) chain A residue 101 type sequence H description BINDING SITE FOR RESIDUE FE A 602 source : AC2 7) chain A residue 127 type sequence D description BINDING SITE FOR RESIDUE FE A 602 source : AC2 8) chain A residue 101 type sequence H description BINDING SITE FOR RESIDUE PO4 A 603 source : AC3 9) chain A residue 127 type sequence D description BINDING SITE FOR RESIDUE PO4 A 603 source : AC3 10) chain A residue 131 type sequence R description BINDING SITE FOR RESIDUE PO4 A 603 source : AC3 11) chain A residue 159 type sequence N description BINDING SITE FOR RESIDUE PO4 A 603 source : AC3 12) chain A residue 160 type sequence H description BINDING SITE FOR RESIDUE PO4 A 603 source : AC3 13) chain A residue 263 type sequence R description BINDING SITE FOR RESIDUE PO4 A 603 source : AC3 14) chain A residue 290 type sequence H description BINDING SITE FOR RESIDUE PO4 A 603 source : AC3 15) chain A residue 156-161 type prosite sequence LRGNHE description SER_THR_PHOSPHATASE Serine/threonine specific protein phosphatases signature. LRGNHE source prosite : PS00125

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