eF-site ID 4oqd-D PDB Code 4oqd Chain D click to enlarge Title Crystal structure of the tylM1 N,N-dimethyltransferase in complex with SAH and TDP-Qui3NMe2 Classification TRANSFERASE Compound dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase Source Streptomyces fradiae (Streptomyces roseoflavus) (TYLM1_STRFR) Sequence D:  PQADYSGEIAELYDLVHQGKGKDYHREAADLAALVRRHSP KAASLLDVACGTGMHLRHLADSFGTVEGLELSADMLAIAR RRNPDAVLHHGDMRDFSLGRRFSAVTCMFSSIGHLAGQAE LDAALERFAAHVLPDGVVVVEPWWFPENFTPGYVAAGTVE AGGTTVTRVSHSSREGEATRIEVHYLVAGPDRGITHHEES HRITLFTREQYERAFTAAGLSVEFMPGGPSGRGLFTGLPG Description Functional site 1) chain D residue 14 type sequence Y description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 2) chain D residue 22 type sequence Y description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 3) chain D residue 33 type sequence Y description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 4) chain D residue 58 type sequence A description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 5) chain D residue 59 type sequence C description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 6) chain D residue 60 type sequence G description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 7) chain D residue 64 type sequence H description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 8) chain D residue 79 type sequence E description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 9) chain D residue 80 type sequence L description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 10) chain D residue 81 type sequence S description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 11) chain D residue 84 type sequence M description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 12) chain D residue 100 type sequence G description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 13) chain D residue 101 type sequence D description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 14) chain D residue 102 type sequence M description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 15) chain D residue 117 type sequence M description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 16) chain D residue 118 type sequence F description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 17) chain D residue 120 type sequence S description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 18) chain D residue 123 type sequence H description BINDING SITE FOR RESIDUE SAH D 300 source : AC7 19) chain D residue 14 type sequence Y description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 20) chain D residue 26 type sequence H description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 21) chain D residue 29 type sequence K description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 22) chain D residue 118 type sequence F description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 23) chain D residue 152 type sequence W description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 24) chain D residue 153 type sequence W description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 25) chain D residue 157 type sequence N description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 26) chain D residue 158 type sequence F description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 27) chain D residue 159 type sequence T description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 28) chain D residue 162 type sequence Y description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 29) chain D residue 177 type sequence R description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 30) chain D residue 179 type sequence S description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 31) chain D residue 181 type sequence S description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 32) chain D residue 190 type sequence I description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 33) chain D residue 210 type sequence H description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 34) chain D residue 241 type sequence R description BINDING SITE FOR RESIDUE QDM D 301 source : AC8 35) chain D residue 14 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 36) chain D residue 22 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 37) chain D residue 33 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 38) chain D residue 58 type BINDING sequence A description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 39) chain D residue 79 type BINDING sequence E description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 40) chain D residue 117 type BINDING sequence M description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 41) chain D residue 101 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI2

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