eF-site ID 4oqd-A PDB Code 4oqd Chain A click to enlarge Title Crystal structure of the tylM1 N,N-dimethyltransferase in complex with SAH and TDP-Qui3NMe2 Classification TRANSFERASE Compound dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase Source Streptomyces fradiae (Streptomyces roseoflavus) (TYLM1_STRFR) Sequence A:  ADYSGEIAELYDLVHQGKGKDYHREAADLAALVRRHSPKA ASLLDVACGTGMHLRHLADSFGTVEGLELSADMLAIARRR NPDAVLHHGDMRDFSLGRRFSAVTCMFSSIGHLAGQAELD AALERFAAHVLPDGVVVVEPWWFPENFTPGYVAAGTVEAG GTTVTRVSHSSREGEATRIEVHYLVAGPDRGITHHEESHR ITLFTREQYERAFTAAGLSVEFMPGGPSGRGLFTGLPGA Description Functional site 1) chain A residue 14 type sequence Y description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 2) chain A residue 22 type sequence Y description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 3) chain A residue 33 type sequence Y description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 4) chain A residue 58 type sequence A description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 5) chain A residue 60 type sequence G description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 6) chain A residue 64 type sequence H description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 7) chain A residue 79 type sequence E description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 8) chain A residue 80 type sequence L description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 9) chain A residue 81 type sequence S description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 10) chain A residue 84 type sequence M description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 11) chain A residue 100 type sequence G description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 12) chain A residue 101 type sequence D description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 13) chain A residue 102 type sequence M description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 14) chain A residue 117 type sequence M description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 15) chain A residue 118 type sequence F description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 16) chain A residue 120 type sequence S description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 17) chain A residue 123 type sequence H description BINDING SITE FOR RESIDUE SAH A 300 source : AC1 18) chain A residue 14 type sequence Y description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 19) chain A residue 26 type sequence H description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 20) chain A residue 29 type sequence K description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 21) chain A residue 118 type sequence F description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 22) chain A residue 152 type sequence W description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 23) chain A residue 153 type sequence W description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 24) chain A residue 157 type sequence N description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 25) chain A residue 158 type sequence F description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 26) chain A residue 159 type sequence T description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 27) chain A residue 162 type sequence Y description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 28) chain A residue 177 type sequence R description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 29) chain A residue 179 type sequence S description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 30) chain A residue 181 type sequence S description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 31) chain A residue 190 type sequence I description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 32) chain A residue 241 type sequence R description BINDING SITE FOR RESIDUE QDM A 301 source : AC2 33) chain A residue 117 type BINDING sequence M description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 34) chain A residue 79 type BINDING sequence E description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 35) chain A residue 14 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 36) chain A residue 22 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 37) chain A residue 33 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 38) chain A residue 58 type BINDING sequence A description BINDING => ECO:0000269|PubMed:21142177 source Swiss-Prot : SWS_FT_FI1 39) chain A residue 101 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI2

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