|
|
eF-site ID
|
4ong-P |
|
PDB Code
|
4ong |
|
Chain
|
P |
|
click to enlarge
|
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Title
|
Fab fragment of 3D6 in complex with amyloid beta 1-40 |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
3D6 FAB ANTIBODY HEAVY CHAIN |
|
Source
|
Homo sapiens (Human) (4ONG) |
|
|
Sequence
|
P: |
DAEFR
|
|
|
Description
|
|
Functional site
|
|
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1)
|
chain |
P |
| residue |
1 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE ZN H 307
|
| source |
: AC7
|
|
|
2)
|
chain |
P |
| residue |
4 |
| type |
|
| sequence |
F
|
| description |
BINDING SITE FOR RESIDUE ZN H 307
|
| source |
: AC7
|
|
|
3)
|
chain |
P |
| residue |
4 |
| type |
|
| sequence |
F
|
| description |
BINDING SITE FOR RESIDUE ZN H 309
|
| source |
: AC9
|
|
|
4)
|
chain |
P |
| residue |
5 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE ZN L 313
|
| source |
: DC6
|
|
|
5)
|
chain |
P |
| residue |
1 |
| type |
SITE |
| sequence |
D
|
| description |
Cleavage; by caspase-6; when associated with variant 670-N-L-671
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|