eF-site ID 4ong-L PDB Code 4ong Chain L click to enlarge Title Fab fragment of 3D6 in complex with amyloid beta 1-40 Classification IMMUNE SYSTEM Compound 3D6 FAB ANTIBODY HEAVY CHAIN Source Homo sapiens (Human) (4ONG) Sequence L:  YVVMTQTPLTLSVTIGQPASISCKSSQSLLDSDGKTYLNW LLQRPGQSPKRLIYLVSKLDSGVPDRFTGSGSGTDFTLKI SRIEAEDLGLYYCWQGTHFPRTFGGGTKLEIKRADAAPTV SIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSER QNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCE ATHKTSPIVKSFNR Description Functional site 1) chain L residue 172 type sequence D description BINDING SITE FOR RESIDUE ZN H 303 source : AC3 2) chain L residue 101 type sequence R description BINDING SITE FOR RESIDUE ZN H 307 source : AC7 3) chain L residue 99 type sequence F description BINDING SITE FOR RESIDUE IMD H 315 source : BC6 4) chain L residue 1 type sequence Y description BINDING SITE FOR RESIDUE ZN L 301 source : CC3 5) chain L residue 98 type sequence H description BINDING SITE FOR RESIDUE ZN L 301 source : CC3 6) chain L residue 194 type sequence H description BINDING SITE FOR RESIDUE ZN L 302 source : CC4 7) chain L residue 115 type sequence D description BINDING SITE FOR RESIDUE ZN L 303 source : CC5 8) chain L residue 115 type sequence D description BINDING SITE FOR RESIDUE ZN L 303 source : CC5 9) chain L residue 203 type sequence H description BINDING SITE FOR RESIDUE ZN L 304 source : CC6 10) chain L residue 170 type sequence D description BINDING SITE FOR RESIDUE ZN L 306 source : CC8 11) chain L residue 154 type sequence K description BINDING SITE FOR RESIDUE ZN L 308 source : DC1 12) chain L residue 200 type sequence E description BINDING SITE FOR RESIDUE ZN L 308 source : DC1 13) chain L residue 84 type sequence E description BINDING SITE FOR RESIDUE ZN L 309 source : DC2 14) chain L residue 157 type sequence G description BINDING SITE FOR RESIDUE ZN L 311 source : DC4 15) chain L residue 196 type sequence S description BINDING SITE FOR RESIDUE ZN L 311 source : DC4 16) chain L residue 175 type sequence D description BINDING SITE FOR RESIDUE ZN L 312 source : DC5 17) chain L residue 31 type sequence D description BINDING SITE FOR RESIDUE ZN L 313 source : DC6 18) chain L residue 143 type sequence N description BINDING SITE FOR RESIDUE ZN L 314 source : DC7 19) chain L residue 172 type sequence D description BINDING SITE FOR RESIDUE ZN L 314 source : DC7 20) chain L residue 9 type sequence L description BINDING SITE FOR RESIDUE IMD L 315 source : DC8 21) chain L residue 105 type sequence G description BINDING SITE FOR RESIDUE IMD L 315 source : DC8 22) chain L residue 106 type sequence G description BINDING SITE FOR RESIDUE IMD L 315 source : DC8 23) chain L residue 116 type sequence A description BINDING SITE FOR RESIDUE CL L 316 source : DC9 24) chain L residue 117 type sequence A description BINDING SITE FOR RESIDUE CL L 316 source : DC9 25) chain L residue 203 type sequence H description BINDING SITE FOR RESIDUE CL L 316 source : DC9 26) chain L residue 203 type sequence H description BINDING SITE FOR RESIDUE CL L 317 source : EC1 27) chain L residue 170 type sequence D description BINDING SITE FOR RESIDUE CL L 318 source : EC2 28) chain L residue 194 type sequence H description BINDING SITE FOR RESIDUE CL L 319 source : EC3 29) chain L residue 194 type sequence H description BINDING SITE FOR RESIDUE CL L 320 source : EC4 30) chain L residue 156 type sequence D description BINDING SITE FOR RESIDUE CL L 321 source : EC5 31) chain L residue 157 type sequence G description BINDING SITE FOR RESIDUE CL L 321 source : EC5 32) chain L residue 196 type sequence S description BINDING SITE FOR RESIDUE CL L 321 source : EC5 33) chain L residue 198 type sequence T description BINDING SITE FOR RESIDUE CL L 321 source : EC5 34) chain L residue 31 type sequence D description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 35) chain L residue 37 type sequence Y description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 36) chain L residue 94 type sequence W description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 37) chain L residue 96 type sequence G description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 38) chain L residue 97 type sequence T description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 39) chain L residue 98 type sequence H description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 40) chain L residue 101 type sequence R description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 41) chain L residue 197-203 type prosite sequence YTCEATH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH source prosite : PS00290

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