eF-site ID 4ong-H PDB Code 4ong Chain H click to enlarge Title Fab fragment of 3D6 in complex with amyloid beta 1-40 Classification IMMUNE SYSTEM Compound 3D6 FAB ANTIBODY HEAVY CHAIN Source Homo sapiens (Human) (4ONG) Sequence H:  EVKLVESGGGLVKPGASLKLSCAASGFTFSNYGMSWVRQN SDKRLEWVASIRSGGGRTYYSDNVKGRFTISRENAKNTLY LQMSSLKSEDTALYYCVRYDSGSSDYWGQGTTVTVSSAKT TPPSVYPLAPSMVTLGCLVKGYFPEPVTVTWNSGSLSSGV HTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASS TKVDKKIVPR Description Functional site 1) chain H residue 213 type sequence D description BINDING SITE FOR RESIDUE ZN H 301 source : AC1 2) chain H residue 213 type sequence D description BINDING SITE FOR RESIDUE ZN H 301 source : AC1 3) chain H residue 62 type sequence D description BINDING SITE FOR RESIDUE ZN H 302 source : AC2 4) chain H residue 170 type sequence H description BINDING SITE FOR RESIDUE ZN H 303 source : AC3 5) chain H residue 1 type sequence E description BINDING SITE FOR RESIDUE ZN H 306 source : AC6 6) chain H residue 179 type sequence D description BINDING SITE FOR RESIDUE ZN H 306 source : AC6 7) chain H residue 65 type sequence K description BINDING SITE FOR RESIDUE ZN H 308 source : AC8 8) chain H residue 113 type sequence T description BINDING SITE FOR RESIDUE ZN H 310 source : BC1 9) chain H residue 214 type sequence K description BINDING SITE FOR RESIDUE ZN H 311 source : BC2 10) chain H residue 44 type sequence R description BINDING SITE FOR RESIDUE ZN H 312 source : BC3 11) chain H residue 46 type sequence E description BINDING SITE FOR RESIDUE ZN H 312 source : BC3 12) chain H residue 200 type sequence T description BINDING SITE FOR RESIDUE IMD H 314 source : BC5 13) chain H residue 209 type sequence S description BINDING SITE FOR RESIDUE IMD H 314 source : BC5 14) chain H residue 211 type sequence K description BINDING SITE FOR RESIDUE IMD H 314 source : BC5 15) chain H residue 215 type sequence K description BINDING SITE FOR RESIDUE IMD H 314 source : BC5 16) chain H residue 60 type sequence Y description BINDING SITE FOR RESIDUE IMD H 315 source : BC6 17) chain H residue 62 type sequence D description BINDING SITE FOR RESIDUE IMD H 315 source : BC6 18) chain H residue 206 type sequence P description BINDING SITE FOR RESIDUE CL H 316 source : BC7 19) chain H residue 161 type sequence N description BINDING SITE FOR RESIDUE CL H 318 source : BC9 20) chain H residue 162 type sequence S description BINDING SITE FOR RESIDUE CL H 318 source : BC9 21) chain H residue 202 type sequence N description BINDING SITE FOR RESIDUE CL H 318 source : BC9 22) chain H residue 211 type sequence K description BINDING SITE FOR RESIDUE CL H 319 source : CC1 23) chain H residue 213 type sequence D description BINDING SITE FOR RESIDUE CL H 319 source : CC1 24) chain H residue 59 type sequence Y description BINDING SITE FOR RESIDUE CL H 320 source : CC2 25) chain H residue 60 type sequence Y description BINDING SITE FOR RESIDUE CL H 320 source : CC2 26) chain H residue 65 type sequence K description BINDING SITE FOR RESIDUE CL H 320 source : CC2 27) chain H residue 65 type sequence K description BINDING SITE FOR RESIDUE CL H 320 source : CC2 28) chain H residue 170 type sequence H description BINDING SITE FOR RESIDUE ZN L 314 source : DC7 29) chain H residue 34 type sequence M description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 30) chain H residue 35 type sequence S description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 31) chain H residue 50 type sequence S description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 32) chain H residue 51 type sequence I description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 33) chain H residue 52 type sequence R description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 34) chain H residue 59 type sequence Y description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 35) chain H residue 99 type sequence Y description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 36) chain H residue 105 type sequence S description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6 37) chain H residue 106 type sequence S description BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN source : EC6

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