eF-site ID 4omk-AB PDB Code 4omk Chain A, B click to enlarge Title Crystal structure of SPF bound to squalene Classification TRANSPORT PROTEIN Compound SEC14-like protein 2 Source Homo sapiens (Human) (S14L2_HUMAN) Sequence A:  MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLR WLRARSFDLQKSEAMLRKHVEFRKQKDIDNIISWQPPEVI QQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGL KHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPV AYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQV B:  MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLR WLRARSFDLQKSEAMLRKHVEFRKQKDIDNIISWQPPEVI QQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGL KHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPV AYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQV Description Functional site 1) chain A residue 116 type sequence S description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 2) chain A residue 117 type sequence K description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 3) chain A residue 118 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 4) chain A residue 195 type sequence P description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 5) chain A residue 196 type sequence K description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 6) chain A residue 188 type sequence R description BINDING SITE FOR RESIDUE SO4 A 303 source : AC3 7) chain A residue 231 type sequence H description BINDING SITE FOR RESIDUE SO4 A 303 source : AC3 8) chain A residue 165 type sequence K description BINDING SITE FOR RESIDUE CL A 304 source : AC4 9) chain A residue 106 type sequence L description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 10) chain A residue 111 type sequence L description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 11) chain A residue 112 type sequence L description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 12) chain A residue 121 type sequence L description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 13) chain A residue 124 type sequence K description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 14) chain A residue 153 type sequence Y description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 15) chain A residue 155 type sequence C description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 16) chain A residue 162 type sequence H description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 17) chain A residue 163 type sequence L description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 18) chain A residue 167 type sequence A description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 19) chain A residue 168 type sequence V description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 20) chain A residue 170 type sequence A description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 21) chain A residue 171 type sequence Y description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 22) chain A residue 198 type sequence F description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 23) chain A residue 201 type sequence A description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 24) chain A residue 202 type sequence Y description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 25) chain A residue 213 type sequence T description BINDING SITE FOR RESIDUE SQL A 305 source : AC5 26) chain A residue 99 type sequence W description BINDING SITE FOR RESIDUE IPA A 306 source : AC6 27) chain A residue 101 type sequence D description BINDING SITE FOR RESIDUE IPA A 306 source : AC6 28) chain A residue 124 type sequence K description BINDING SITE FOR RESIDUE IPA A 306 source : AC6 29) chain A residue 127 type sequence E description BINDING SITE FOR RESIDUE IPA A 306 source : AC6 30) chain B residue 116 type sequence S description BINDING SITE FOR RESIDUE SO4 B 301 source : AC7 31) chain B residue 117 type sequence K description BINDING SITE FOR RESIDUE SO4 B 301 source : AC7 32) chain B residue 118 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 301 source : AC7 33) chain A residue 206 type sequence K description BINDING SITE FOR RESIDUE SO4 B 302 source : AC8 34) chain B residue 165 type sequence K description BINDING SITE FOR RESIDUE SO4 B 302 source : AC8 35) chain B residue 188 type sequence R description BINDING SITE FOR RESIDUE SO4 B 303 source : AC9 36) chain B residue 231 type sequence H description BINDING SITE FOR RESIDUE SO4 B 303 source : AC9 37) chain B residue 255 type sequence K description BINDING SITE FOR RESIDUE CL B 304 source : BC1 38) chain B residue 108 type sequence A description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 39) chain B residue 111 type sequence L description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 40) chain B residue 124 type sequence K description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 41) chain B residue 153 type sequence Y description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 42) chain B residue 162 type sequence H description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 43) chain B residue 167 type sequence A description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 44) chain B residue 170 type sequence A description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 45) chain B residue 171 type sequence Y description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 46) chain B residue 175 type sequence L description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 47) chain B residue 198 type sequence F description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 48) chain B residue 201 type sequence A description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 49) chain B residue 202 type sequence Y description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 50) chain B residue 205 type sequence I description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 51) chain B residue 213 type sequence T description BINDING SITE FOR RESIDUE SQL B 305 source : BC2 52) chain B residue 101 type sequence D description BINDING SITE FOR RESIDUE IPA B 306 source : BC3 53) chain B residue 124 type sequence K description BINDING SITE FOR RESIDUE IPA B 306 source : BC3 54) chain B residue 127 type sequence E description BINDING SITE FOR RESIDUE IPA B 306 source : BC3 55) chain A residue 51 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1 56) chain A residue 253 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1 57) chain A residue 257 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1 58) chain B residue 51 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1 59) chain B residue 253 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1 60) chain B residue 257 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1

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