eF-site ID 4omj-AB PDB Code 4omj Chain A, B click to enlarge Title Crystal structure of SPF bound to 2,3-oxidosqualene Classification TRANSPORT PROTEIN Compound SEC14-like protein 2 Source Homo sapiens (Human) (S14L2_HUMAN) Sequence A:  MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLR WLRARSFDLQKSEAMLRKHVEFRKQKDIDNIISWQPPEVI QQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGL KHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPV AYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQV B:  MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLR WLRARSFDLQKSEAMLRKHVEFRKQKDIDNIISWQPPEVI QQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGL KHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPV AYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQV Description Functional site 1) chain A residue 116 type sequence S description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 2) chain A residue 117 type sequence K description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 3) chain A residue 118 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 4) chain A residue 195 type sequence P description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 5) chain A residue 196 type sequence K description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 6) chain A residue 251 type sequence N description BINDING SITE FOR RESIDUE SO4 A 303 source : AC3 7) chain A residue 253 type sequence K description BINDING SITE FOR RESIDUE SO4 A 303 source : AC3 8) chain A residue 255 type sequence K description BINDING SITE FOR RESIDUE SO4 A 303 source : AC3 9) chain A residue 188 type sequence R description BINDING SITE FOR RESIDUE CL A 304 source : AC4 10) chain A residue 165 type sequence K description BINDING SITE FOR RESIDUE CL A 305 source : AC5 11) chain B residue 206 type sequence K description BINDING SITE FOR RESIDUE CL A 305 source : AC5 12) chain B residue 214 type sequence R description BINDING SITE FOR RESIDUE CL A 305 source : AC5 13) chain A residue 214 type sequence R description BINDING SITE FOR RESIDUE CL A 306 source : AC6 14) chain B residue 165 type sequence K description BINDING SITE FOR RESIDUE CL A 306 source : AC6 15) chain A residue 266 type sequence R description BINDING SITE FOR RESIDUE CL A 307 source : AC7 16) chain A residue 203 type sequence N description BINDING SITE FOR RESIDUE CL A 308 source : AC8 17) chain B residue 164 type sequence W description BINDING SITE FOR RESIDUE CL A 308 source : AC8 18) chain B residue 165 type sequence K description BINDING SITE FOR RESIDUE CL A 308 source : AC8 19) chain A residue 78 type sequence E description BINDING SITE FOR RESIDUE CL A 309 source : AC9 20) chain A residue 268 type sequence Y description BINDING SITE FOR RESIDUE CL A 309 source : AC9 21) chain A residue 108 type sequence A description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 22) chain A residue 121 type sequence L description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 23) chain A residue 153 type sequence Y description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 24) chain A residue 155 type sequence C description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 25) chain A residue 162 type sequence H description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 26) chain A residue 167 type sequence A description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 27) chain A residue 170 type sequence A description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 28) chain A residue 171 type sequence Y description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 29) chain A residue 175 type sequence L description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 30) chain A residue 189 type sequence L description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 31) chain A residue 198 type sequence F description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 32) chain A residue 202 type sequence Y description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 33) chain A residue 205 type sequence I description BINDING SITE FOR RESIDUE 2TX A 310 source : BC1 34) chain B residue 116 type sequence S description BINDING SITE FOR RESIDUE SO4 B 301 source : BC2 35) chain B residue 117 type sequence K description BINDING SITE FOR RESIDUE SO4 B 301 source : BC2 36) chain B residue 118 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 301 source : BC2 37) chain B residue 195 type sequence P description BINDING SITE FOR RESIDUE SO4 B 302 source : BC3 38) chain B residue 196 type sequence K description BINDING SITE FOR RESIDUE SO4 B 302 source : BC3 39) chain B residue 188 type sequence R description BINDING SITE FOR RESIDUE SO4 B 303 source : BC4 40) chain B residue 231 type sequence H description BINDING SITE FOR RESIDUE SO4 B 303 source : BC4 41) chain B residue 251 type sequence N description BINDING SITE FOR RESIDUE SO4 B 304 source : BC5 42) chain B residue 253 type sequence K description BINDING SITE FOR RESIDUE SO4 B 304 source : BC5 43) chain B residue 255 type sequence K description BINDING SITE FOR RESIDUE SO4 B 304 source : BC5 44) chain B residue 266 type sequence R description BINDING SITE FOR RESIDUE CL B 305 source : BC6 45) chain B residue 105 type sequence P description BINDING SITE FOR RESIDUE CL B 306 source : BC7 46) chain B residue 262 type sequence G description BINDING SITE FOR RESIDUE CL B 306 source : BC7 47) chain B residue 263 type sequence D description BINDING SITE FOR RESIDUE CL B 306 source : BC7 48) chain B residue 221 type sequence G description BINDING SITE FOR RESIDUE CL B 307 source : BC8 49) chain B residue 222 type sequence A description BINDING SITE FOR RESIDUE CL B 307 source : BC8 50) chain B residue 106 type sequence L description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 51) chain B residue 111 type sequence L description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 52) chain B residue 124 type sequence K description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 53) chain B residue 153 type sequence Y description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 54) chain B residue 155 type sequence C description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 55) chain B residue 162 type sequence H description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 56) chain B residue 167 type sequence A description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 57) chain B residue 175 type sequence L description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 58) chain B residue 189 type sequence L description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 59) chain B residue 198 type sequence F description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 60) chain B residue 202 type sequence Y description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 61) chain B residue 205 type sequence I description BINDING SITE FOR RESIDUE 2TX B 308 source : BC9 62) chain A residue 51 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1 63) chain A residue 253 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1 64) chain A residue 257 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1 65) chain B residue 51 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1 66) chain B residue 253 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1 67) chain B residue 257 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99J08 source Swiss-Prot : SWS_FT_FI1

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