eF-site ID 4oma-A PDB Code 4oma Chain A click to enlarge Title The crystal structure of methionine gamma-lyase from Citrobacter freundii in complex with L-cycloserine pyridoxal-5'-phosphate Classification LYASE Compound methionine gamma-lyase Source Citrobacter freundii GTC 09629 (R1FPL7_CITFR) Sequence A:  SDCRTYGFNTQIVHAGQQPDPSTGALSTPIFQTSTFVFDS AEQGAARFALEESGYIYTRLGNPTTDALEKKLAVLERGEA GLATASGISAITTTLLTLCQQGDHIVSASAIYGCTHAFLS HSMPKFGINVSFVDAAKPEEIRAAMRPETKVVYIETPANP TLSLVDIETVAGIAHQQGALLVVDNTFMSPYCQQPLQLGA DIVVHSVTKYINGHGDVIGGIIVGKQEFIDQARFVGLKDI TGGCMSPFNAWLTLRGVKTLGIRMERHCENALKIARFLEG HPSITRVYYPGLSSHPQYELGQRQMSLPGGIISFEIAGGL EAGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPVAPE ERLKAGITDGLIRLSVGLEDPEDIINDLEHAIRKAT Description Functional site 1) chain A residue 58 type sequence Y description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 2) chain A residue 60 type sequence R description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 3) chain A residue 87 type sequence S description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 4) chain A residue 88 type sequence G description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 5) chain A residue 89 type sequence I description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 6) chain A residue 113 type sequence Y description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 7) chain A residue 185 type sequence D description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 8) chain A residue 187 type sequence T description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 9) chain A residue 207 type sequence S description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 10) chain A residue 209 type sequence T description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 11) chain A residue 210 type sequence K description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 12) chain A residue 338 type sequence V description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 13) chain A residue 339 type sequence S description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 14) chain A residue 340 type sequence L description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 15) chain A residue 374 type sequence R description BINDING SITE FOR RESIDUE LCS A 401 source : AC1 16) chain A residue 191 type sequence P description BINDING SITE FOR RESIDUE PGE A 402 source : AC2 17) chain A residue 192 type sequence Y description BINDING SITE FOR RESIDUE PGE A 402 source : AC2 18) chain A residue 303 type sequence Q description BINDING SITE FOR RESIDUE PGE A 402 source : AC2 19) chain A residue 305 type sequence Q description BINDING SITE FOR RESIDUE PGE A 402 source : AC2 20) chain A residue 307 type sequence S description BINDING SITE FOR RESIDUE PGE A 402 source : AC2 21) chain A residue 270 type sequence E description BINDING SITE FOR RESIDUE PGE A 403 source : AC3 22) chain A residue 274 type sequence K description BINDING SITE FOR RESIDUE PGE A 403 source : AC3 23) chain A residue 383 type sequence E description BINDING SITE FOR RESIDUE PGE A 403 source : AC3 24) chain A residue 277 type sequence R description BINDING SITE FOR RESIDUE PEG A 404 source : AC4 25) chain A residue 280 type sequence E description BINDING SITE FOR RESIDUE PEG A 404 source : AC4 26) chain A residue 292 type sequence G description BINDING SITE FOR RESIDUE PEG A 404 source : AC4 27) chain A residue 293 type sequence L description BINDING SITE FOR RESIDUE PEG A 404 source : AC4 28) chain A residue 294 type sequence S description BINDING SITE FOR RESIDUE PEG A 404 source : AC4 29) chain A residue 295 type sequence S description BINDING SITE FOR RESIDUE PEG A 404 source : AC4 30) chain A residue 9 type sequence F description BINDING SITE FOR RESIDUE PEG A 405 source : AC5 31) chain A residue 192 type sequence Y description BINDING SITE FOR RESIDUE PEG A 405 source : AC5 32) chain A residue 266 type sequence E description BINDING SITE FOR RESIDUE PEG A 405 source : AC5 33) chain A residue 307 type sequence S description BINDING SITE FOR RESIDUE PEG A 405 source : AC5 34) chain A residue 271 type sequence N description BINDING SITE FOR RESIDUE CL A 406 source : AC6 35) chain A residue 378 type sequence G description BINDING SITE FOR RESIDUE CL A 406 source : AC6 36) chain A residue 380 type sequence E description BINDING SITE FOR RESIDUE CL A 406 source : AC6 37) chain A residue 385 type sequence I description BINDING SITE FOR RESIDUE CL A 406 source : AC6

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