|
|
eF-site ID
|
4oir-B |
|
PDB Code
|
4oir |
|
Chain
|
B |
|
click to enlarge
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Title
|
Crystal structure of Thermus thermophilus RNA polymerase transcription initiation complex soaked with GE23077 and rifamycin SV |
|
Classification
|
TRANSCRIPTION, TRANSFERASE/ANTIBIOTIC |
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Compound
|
DNA-directed RNA polymerase subunit alpha |
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Source
|
ORGANISM_SCIENTIFIC: Thermus thermophilus; |
|
|
Sequence
|
B: |
LDSKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPLR
RILLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIILN
LKELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADVE
IMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKDR
INAIPVDAVFSPVRRVAFQVEDTRLGQRTDLDKLTLRIWT
DGSVTPLEALNQAVEILREHLTYFSNP
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
154 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE MG B 401
|
| source |
: AC1
|
|
|
2)
|
chain |
B |
| residue |
168 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG B 401
|
| source |
: AC1
|
|
|
3)
|
chain |
B |
| residue |
8 |
| type |
|
| sequence |
A
|
| description |
BINDING SITE FOR GE23077
|
| source |
: AC8
|
|
|
4)
|
chain |
B |
| residue |
9 |
| type |
|
| sequence |
P
|
| description |
BINDING SITE FOR GE23077
|
| source |
: AC8
|
|
|
5)
|
chain |
B |
| residue |
29 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR GE23077
|
| source |
: AC8
|
|
|
6)
|
chain |
B |
| residue |
189 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR GE23077
|
| source |
: AC8
|
|
|
|