eF-site ID 4odf-A PDB Code 4odf Chain A click to enlarge Title Co-Crystal Structure of MDM2 with Inhibitor Compound 47 Classification LIGASE/LIGASE INHIBITOR Compound E3 ubiquitin-protein ligase Mdm2 Source Homo sapiens (Human) (MDM2_HUMAN) Sequence A:  GAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMK EVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSF SVKEHRKIYTMIYRNLVVV Description Functional site 1) chain A residue 14 type sequence V description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 2) chain A residue 16 type sequence T description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 3) chain A residue 17 type sequence S description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 4) chain A residue 23 type sequence E description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 5) chain A residue 54 type sequence L description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 6) chain A residue 57 type sequence L description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 7) chain A residue 58 type sequence G description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 8) chain A residue 61 type sequence I description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 9) chain A residue 62 type sequence M description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 10) chain A residue 67 type sequence Y description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 11) chain A residue 93 type sequence V description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 12) chain A residue 96 type sequence H description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 13) chain A residue 99 type sequence I description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 14) chain A residue 100 type sequence Y description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1 15) chain A residue 104 type sequence Y description BINDING SITE FOR RESIDUE 2U1 A 201 source : AC1

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