eF-site ID 4oas-E PDB Code 4oas Chain E click to enlarge Title co-crystal structure of MDM2 (17-111) in complex with compound 25 Classification ligase/ligase inhibitor Compound E3 ubiquitin-protein ligase Mdm2 Source Homo sapiens (Human) (MDM2_HUMAN) Sequence E:  QIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYL GQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHR KIYTMIYRNLVVV Description Functional site 1) chain E residue 97 type sequence R description BINDING SITE FOR RESIDUE 2SW A 201 source : AC1 2) chain E residue 54 type sequence L description BINDING SITE FOR RESIDUE 2SW E 201 source : AC3 3) chain E residue 59 type sequence Q description BINDING SITE FOR RESIDUE 2SW E 201 source : AC3 4) chain E residue 61 type sequence I description BINDING SITE FOR RESIDUE 2SW E 201 source : AC3 5) chain E residue 62 type sequence M description BINDING SITE FOR RESIDUE 2SW E 201 source : AC3 6) chain E residue 93 type sequence V description BINDING SITE FOR RESIDUE 2SW E 201 source : AC3 7) chain E residue 94 type sequence K description BINDING SITE FOR RESIDUE 2SW E 201 source : AC3 8) chain E residue 96 type sequence H description BINDING SITE FOR RESIDUE 2SW E 201 source : AC3 9) chain E residue 100 type sequence Y description BINDING SITE FOR RESIDUE 2SW E 201 source : AC3 10) chain E residue 51 type sequence K description BINDING SITE FOR RESIDUE SO4 E 202 source : AC4

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