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eF-site ID
|
4o9c-A |
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PDB Code
|
4o9c |
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Chain
|
A |
|
click to enlarge
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Title
|
Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16 |
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Classification
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TRANSFERASE |
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Compound
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Acetyl-CoA acetyltransferase |
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Source
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Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha) (THIL_CUPNH) |
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Sequence
|
A: |
MTDVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALER
AGVKPEQVSEVIMGQVLTAGSGQNPARQAAIKAGLPAMVP
AMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGGQENMSA
APHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGIT
AENVAKEYGITREAQDEFAVGSQNKAEAAQKAGKFDEEIV
PVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAFDKAG
TVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYA
NAGVDPKVMGMGPVPASKRALSRAEWTPQDLDLMEINEAF
AAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILV
TLLHEMKRRDAKKGLASLCIGGGMGVALAVERK
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Description
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Functional site
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|
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1)
|
chain |
A |
| residue |
349 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10020, ECO:0000305|PubMed:25152395
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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2)
|
chain |
A |
| residue |
379 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10020, ECO:0000305|PubMed:25152395
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
A |
| residue |
374-387 |
| type |
prosite |
| sequence |
GLASLCIGGGMGVA
|
| description |
THIOLASE_3 Thiolases active site. GLASLCIGgGmGvA
|
| source |
prosite : PS00099
|
|
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4)
|
chain |
A |
| residue |
339-355 |
| type |
prosite |
| sequence |
NVNGGAIAIGHPIGASG
|
| description |
THIOLASE_2 Thiolases signature 2. NvnGGaIAiGHPiGaSG
|
| source |
prosite : PS00737
|
|
|
5)
|
chain |
A |
| residue |
88 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
Acyl-thioester intermediate => ECO:0000269|PubMed:25152395
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|