eF-site ID 4o4l-A PDB Code 4o4l Chain A click to enlarge Title Tubulin-Peloruside A-Epothilone A complex Classification CELL CYCLE/INHIBITOR Compound Tubulin alpha-1B chain Source ORGANISM_COMMON: bovine,cow,domestic cattle,domestic cow; ORGANISM_SCIENTIFIC: Bos taurus; Sequence A:  MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDK TIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRT GTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVD YGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDC AFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEK AYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYR GDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYA KRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS Description Functional site 1) chain A residue 10 type sequence G description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 2) chain A residue 11 type sequence Q description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 3) chain A residue 12 type sequence A description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 4) chain A residue 15 type sequence Q description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 5) chain A residue 98 type sequence D description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 6) chain A residue 99 type sequence A description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 7) chain A residue 100 type sequence A description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 8) chain A residue 101 type sequence N description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 9) chain A residue 140 type sequence S description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 10) chain A residue 143 type sequence G description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 11) chain A residue 144 type sequence G description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 12) chain A residue 145 type sequence T description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 13) chain A residue 146 type sequence G description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 14) chain A residue 177 type sequence V description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 15) chain A residue 183 type sequence E description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 16) chain A residue 206 type sequence N description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 17) chain A residue 224 type sequence Y description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 18) chain A residue 228 type sequence N description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 19) chain A residue 231 type sequence I description BINDING SITE FOR RESIDUE GTP A 501 source : AC1 20) chain A residue 39 type sequence D description BINDING SITE FOR RESIDUE CA A 503 source : AC3 21) chain A residue 41 type sequence T description BINDING SITE FOR RESIDUE CA A 503 source : AC3 22) chain A residue 44 type sequence G description BINDING SITE FOR RESIDUE CA A 503 source : AC3 23) chain A residue 55 type sequence E description BINDING SITE FOR RESIDUE CA A 503 source : AC3 24) chain A residue 326 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P68363 source Swiss-Prot : SWS_FT_FI12 25) chain A residue 370 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P68363 source Swiss-Prot : SWS_FT_FI12 26) chain A residue 140 type BINDING sequence S description BINDING => ECO:0000250|UniProtKB:P68363 source Swiss-Prot : SWS_FT_FI2 27) chain A residue 144 type BINDING sequence G description BINDING => ECO:0000250|UniProtKB:P68363 source Swiss-Prot : SWS_FT_FI2 28) chain A residue 145 type BINDING sequence T description BINDING => ECO:0000250|UniProtKB:P68363 source Swiss-Prot : SWS_FT_FI2 29) chain A residue 179 type BINDING sequence T description BINDING => ECO:0000250|UniProtKB:P68363 source Swiss-Prot : SWS_FT_FI2 30) chain A residue 206 type BINDING sequence N description BINDING => ECO:0000250|UniProtKB:P68363 source Swiss-Prot : SWS_FT_FI2 31) chain A residue 228 type BINDING sequence N description BINDING => ECO:0000250|UniProtKB:P68363 source Swiss-Prot : SWS_FT_FI2 32) chain A residue 142-148 type prosite sequence GGGTGSG description TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG source prosite : PS00227

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