eF-site ID 4o4i-F PDB Code 4o4i Chain F click to enlarge Title Tubulin-Laulimalide-Epothilone A complex Classification CELL CYCLE/INHIBITOR Compound Tubulin alpha-1B chain Source ORGANISM_COMMON: bovine,cow,domestic cattle,domestic cow; ORGANISM_SCIENTIFIC: Bos taurus; Sequence F:  MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLM LGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKL IKTSPELSESCTWFPESYVIYPTNLTDEREVFLAAYNRRR EGREGNVWIAKSSAGAKGEGILISSEASELLDFIDEQGQV HVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREG VLRTSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEG NEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIE PAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACA QKLYAELCQGIVDVAISSVFPLAPTSIFIKL Description Functional site 1) chain F residue 74 type sequence K description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 2) chain F residue 148 type sequence I description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 3) chain F residue 150 type sequence K description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 4) chain F residue 183 type sequence Q description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 5) chain F residue 184 type sequence K description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 6) chain F residue 185 type sequence Y description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 7) chain F residue 186 type sequence L description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 8) chain F residue 198 type sequence K description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 9) chain F residue 241 type sequence T description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 10) chain F residue 242 type sequence N description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 11) chain F residue 318 type sequence D description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 12) chain F residue 330 type sequence I description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 13) chain F residue 331 type sequence E description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 14) chain F residue 333 type sequence N description BINDING SITE FOR RESIDUE ACP F 500 source : BC8 15) chain F residue 202 type sequence R description BINDING SITE FOR RESIDUE MG F 501 source : BC9 16) chain F residue 222 type sequence R description BINDING SITE FOR RESIDUE MG F 501 source : BC9 17) chain F residue 318 type sequence D description BINDING SITE FOR RESIDUE MG F 501 source : BC9 18) chain F residue 331 type sequence E description BINDING SITE FOR RESIDUE MG F 501 source : BC9

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