eF-site ID 4nug-HL PDB Code 4nug Chain H, L click to enlarge Title Crystal structure of HIV-1 broadly neutralizing antibody PGT151 Classification IMMUNE SYSTEM Compound PGT151 light chain Source Homo sapiens (Human) (S6BAM6_HUMAN) Sequence H:  RVQLVESGGGVVQPGKSVRLSCVVSDFPFSKYPMYWVRQA PGKGLEWVAAISGDAWHVVYSNSVQGRFLVSRDNVKNTLY LEMNSLKIEDTAVYRCARMFQESGPPRLDRWSGRNYYYYS GMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAAL GCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSL SSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK L:  DIVMTQTPLSLSVTPGQPASISCKSSESLRQSNGKTSLYW YRQKPGQSPQLLVFEVSNRFSGVSDRFVGSGSGTDFTLRI SRVEAEDVGFYYCMQSKDFPLTFGGGTKVDLKRTVAAPSV FIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQ SGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE VTHQGLSSPVTKSFNRGE Description Functional site 1) chain H residue 55 type sequence W description BINDING SITE FOR RESIDUE P6G L 301 source : AC1 2) chain H residue 133 type sequence T description BINDING SITE FOR RESIDUE P6G L 301 source : AC1 3) chain H residue 134 type sequence S description BINDING SITE FOR RESIDUE P6G L 301 source : AC1 4) chain L residue 113 type sequence P description BINDING SITE FOR RESIDUE P6G L 301 source : AC1 5) chain L residue 114 type sequence S description BINDING SITE FOR RESIDUE P6G L 301 source : AC1 6) chain L residue 115 type sequence V description BINDING SITE FOR RESIDUE P6G L 301 source : AC1 7) chain L residue 205 type sequence V description BINDING SITE FOR RESIDUE P6G L 301 source : AC1 8) chain L residue 207 type sequence K description BINDING SITE FOR RESIDUE P6G L 301 source : AC1 9) chain H residue 8 type sequence G description BINDING SITE FOR RESIDUE P6G H 301 source : AC2 10) chain H residue 9 type sequence G description BINDING SITE FOR RESIDUE P6G H 301 source : AC2 11) chain H residue 10 type sequence G description BINDING SITE FOR RESIDUE P6G H 301 source : AC2 12) chain H residue 11 type sequence V description BINDING SITE FOR RESIDUE P6G H 301 source : AC2 13) chain H residue 74 type sequence V description BINDING SITE FOR RESIDUE P6G H 301 source : AC2 14) chain H residue 75 type sequence K description BINDING SITE FOR RESIDUE P6G H 301 source : AC2 15) chain H residue 196 type sequence S description BINDING SITE FOR RESIDUE P6G H 301 source : AC2 16) chain H residue 197 type sequence S description BINDING SITE FOR RESIDUE P6G H 301 source : AC2 17) chain H residue 200 type sequence T description BINDING SITE FOR RESIDUE P6G H 301 source : AC2 18) chain H residue 206-212 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290 19) chain L residue 192-198 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290

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