eF-site ID 4nr7-A PDB Code 4nr7 Chain A click to enlarge Title Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand Classification TRANSFERASE Compound CREB-binding protein Source Homo sapiens (Human) (CBP_HUMAN) Sequence A:  KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLG IPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMF NNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG Description Functional site 1) chain A residue 1091 type sequence R description BINDING SITE FOR RESIDUE EDO A 1201 source : AC1 2) chain A residue 1095 type sequence M description BINDING SITE FOR RESIDUE EDO A 1201 source : AC1 3) chain A residue 1096 type sequence P description BINDING SITE FOR RESIDUE EDO A 1201 source : AC1 4) chain A residue 1124 type sequence D description BINDING SITE FOR RESIDUE EDO A 1201 source : AC1 5) chain A residue 1141 type sequence K description BINDING SITE FOR RESIDUE EDO A 1202 source : AC2 6) chain A residue 1146 type sequence Q description BINDING SITE FOR RESIDUE EDO A 1202 source : AC2 7) chain A residue 1107 type sequence E description BINDING SITE FOR RESIDUE EDO A 1203 source : AC3 8) chain A residue 1162 type sequence N description BINDING SITE FOR RESIDUE EDO A 1203 source : AC3 9) chain A residue 1165 type sequence W description BINDING SITE FOR RESIDUE EDO A 1203 source : AC3 10) chain A residue 1166 type sequence L description BINDING SITE FOR RESIDUE EDO A 1203 source : AC3 11) chain A residue 1109 type sequence L description BINDING SITE FOR RESIDUE 2LO A 1204 source : AC4 12) chain A residue 1110 type sequence P description BINDING SITE FOR RESIDUE 2LO A 1204 source : AC4 13) chain A residue 1115 type sequence V description BINDING SITE FOR RESIDUE 2LO A 1204 source : AC4 14) chain A residue 1120 type sequence L description BINDING SITE FOR RESIDUE 2LO A 1204 source : AC4 15) chain A residue 1122 type sequence I description BINDING SITE FOR RESIDUE 2LO A 1204 source : AC4 16) chain A residue 1125 type sequence Y description BINDING SITE FOR RESIDUE 2LO A 1204 source : AC4 17) chain A residue 1168 type sequence N description BINDING SITE FOR RESIDUE 2LO A 1204 source : AC4 18) chain A residue 1173 type sequence R description BINDING SITE FOR RESIDUE 2LO A 1204 source : AC4 19) chain A residue 1174 type sequence V description BINDING SITE FOR RESIDUE 2LO A 1204 source : AC4 20) chain A residue 1177 type sequence F description BINDING SITE FOR RESIDUE 2LO A 1204 source : AC4 21) chain A residue 1108-1167 type prosite sequence SLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQY QEPWQYVDDVWLMFNNAWLY description BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY source prosite : PS00633

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