eF-site ID 4no9-V PDB Code 4no9 Chain V click to enlarge Title yCP in complex with Z-Leu-Leu-Leu-epoxyketone Classification HYDROLASE/HYDROLASE Inhibitor Compound Proteasome subunit alpha type-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence V:  TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPK IWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSAL QMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ AGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQ KSYKFPRGTTAVLKESIVNICD Description Functional site 1) chain V residue 1 type sequence T description BINDING SITE FOR RESIDUE 2LR V 301 source : AC8 2) chain V residue 20 type sequence S description BINDING SITE FOR RESIDUE 2LR V 301 source : AC8 3) chain V residue 21 type sequence T description BINDING SITE FOR RESIDUE 2LR V 301 source : AC8 4) chain V residue 22 type sequence Q description BINDING SITE FOR RESIDUE 2LR V 301 source : AC8 5) chain V residue 27 type sequence A description BINDING SITE FOR RESIDUE 2LR V 301 source : AC8 6) chain V residue 45 type sequence G description BINDING SITE FOR RESIDUE 2LR V 301 source : AC8 7) chain V residue 47 type sequence G description BINDING SITE FOR RESIDUE 2LR V 301 source : AC8 8) chain V residue 49 type sequence A description BINDING SITE FOR RESIDUE 2LR V 301 source : AC8 9) chain V residue 168 type sequence G description BINDING SITE FOR RESIDUE 2LR V 301 source : AC8 10) chain V residue 163 type sequence I description BINDING SITE FOR RESIDUE MG V 302 source : AC9 11) chain V residue 164 type sequence W description BINDING SITE FOR RESIDUE MG V 302 source : AC9 12) chain V residue 166 type sequence D description BINDING SITE FOR RESIDUE MG V 302 source : AC9 13) chain V residue 169 type sequence S description BINDING SITE FOR RESIDUE MG V 302 source : AC9 14) chain V residue 1 type catalytic sequence T description 177 source MCSA : MCSA2 15) chain V residue 17 type catalytic sequence D description 177 source MCSA : MCSA2 16) chain V residue 19 type catalytic sequence R description 177 source MCSA : MCSA2 17) chain V residue 33 type catalytic sequence K description 177 source MCSA : MCSA2 18) chain V residue 47 type catalytic sequence G description 177 source MCSA : MCSA2 19) chain V residue 129 type catalytic sequence S description 177 source MCSA : MCSA2 20) chain V residue 166 type catalytic sequence D description 177 source MCSA : MCSA2 21) chain V residue 169 type catalytic sequence S description 177 source MCSA : MCSA2

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